Proteasome inhibitors and their combination with antiandrogens: effects on apoptosis, cellular proliferation and viability of prostatic adenocarcinoma cell cultures

Autor: T Zwergel, A Tahmatzopoulos, G Unteregger, B Wullich, U. Zwergel, Michael Stöckle

Publikováno v: Prostate Cancer and Prostatic Diseases. 7:138-143

The 26S proteasome is a ubiquitin-dependent proteolytic system that has been implicated in the regulation of cell cycle progression and apoptosis. We investigated the effects of the proteasome inhibitors MG115 and PSI alone or in combination with dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149b0c07d47b718cf33d8c8e2316121f
https://doi.org/10.1038/sj.pcan.4500709

FOCAL INTRATUMORAL HETEROGENEITY FOR TELOMERASE ACTIVITY IN HUMAN PROSTATE CANCER

Autor: Ralf Ketter, Volker Rohde, H.-P. Sattler, B Oehlenschläger, Helmut Bonkhoff, Bernd Wullich, T. Zwergel

Publikováno v: Journal of Urology. 161:1997-2001

Purpose: The value of telomerase activity as a marker in clinical decision-making is closely related to how representative the analysis of a small tumor sample is for the whole tumor. We therefore evaluated the intratumoral distribution pattern of te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce6b03d9e8ffbcc5a7c417c95363e86
https://doi.org/10.1016/s0022-5347(05)68872-6

Unerwünschte Pharmakaeffekte am unteren Harntrakt und bei der Therapie von Miktionsstörungen

Autor: V. Rohde, Bernd Wullich, T. Zwergel, Ulrike Zwergel

Publikováno v: Der Urologe B. 36:449-453

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26a71ea5400a94864665e09bead03b40
https://doi.org/10.1007/s001310050048

Contents, Vol. 48, 1992

Autor: Toshiki Tanikawa, A.K. Goswami, Tohru Hashimoto, A. Akdaş, H. Van Poppel, Motonobu Nakamura, Kazuo Waskiyama, A. Costa-Bauzá, Isoji Sasagawa, Toyofumi Veda, M. Bolkier, L. Baert, James M. Steckelberg, Rainer Hofmann, D. Gobet, M. Takada, Atsuo Kondo, Keiichi Yokoi, D. Hauri, R. Nath, Naoya Masumori, Toru Sasagawa, M. Iguchi, Giuseppe Capizzi, M.O. Savage, M.P. Wirth, Arno Ebner, G. Zünd, Y. Vardi, Atsushi Takahashi, Noriomi Miyao, Hiroyuki Watanabe, Yasuo Kitamura, Y. Ilker, Walter Artibani, K.D. Zang, G. Seitz, F. Şimşek, K. Lännergren, Koji Miyake, Taiji Tsukamoto, M. Pery, A.-C. Eklöf, Orso, Lucio Laurini, Dino Lavelli, Riccardo Zennari, Takashi Ide, Yoshiharu Oaki, N. Amasaki, Pauline K.W. Yu, Ken Izumiya, K. Mellon, Roy Choudhary, Hiroshi Miyamoto, L. Verhamme, S.K. Thind, Yoko Kubota, B.D. Radotra, C. Genestar, Y. Ishikawa, Antonie Lehmer, Shigeru Kanda, S. Sharma, M. Ahmadzadeh, Hiroshi Susuki, T. Kurita, T. Breitkreuz, Manabu Ishigooka, Shotaro Sato, Jiro Uozumi, Tadashi Ando, Yoshiaki Kumamoto, Joichi Kumazawa, Teruhiro Nakada, M. Theiss, Fukushima S, Hiroaki Kobayashi, A. Conte, Tsutomu Nishiyama, Edeltraud Gürster, Hirotada Mineyama, J.M.W. Kirk, F. Blefari, Masaaki Satoh, S. Josephson, Seizou Sakanishi, Kanefusa Kato, Osamu Kuwamitsu, B. Kreienbühl, Osamu Takahara, D. Ersev, Giuseppe Costa, David E. Neal, Hiroshi Fujii, Jinyu Sano, Soichiro Hasegawa, Eugenio Dall, S.A.V. Holmes, R. Indudhara, Munehisa Takashi, Kiyohito Yamazaki, Rudolf Hartung, O. Risi, Michael R. Keating, Ö. Dillioglugil, Franz Allerberger, Yuichi Adachi, Venetia R. Sarode, Manfred P. Dierich, R.S. Kirby, Fulvio di Torino, K. Kohri, B. Moskovitz, T. Umekawa, S. Liu, Koji Obata, H.G.W. Frohmüller, T. Yamate, P. Pino, S. Vaidyanathan, B. Wullich, Yuanyuan Zhu, T. Zwergel, Masatoshi Moriyama, D.R. Levin, G. Unteregger, Masahiro Yanase, W. Dölken, John P. Anhalt, Noriyuki Otani, F. Grases

Publikováno v: Urologia Internationalis. 48:I-VI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e410c886847c69045a9b5a1e41522d7
https://doi.org/10.1159/000282448

Effects of prostaglandin synthetase inhibitors on the upper urinary tract

Autor: Manfred Ziegler, D. Neisius, T. Zwergel, Ulrike Zwergel

Publikováno v: Urological Research. 18:429-433

Prostaglandin inhibitors such as indomethacin have been used for the treatment of renal colic. While opioids have a central analgesic effect, the effects of indomethacin are mainly peripheral, acting directly on the kidney. Pharmacourodynamic investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd6f915633665e15752e46b9cb60a6b
https://doi.org/10.1007/bf00297379