Zobrazeno 1 - 2
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pro vyhledávání: '"T W, Lipinskas"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(8)
The effects of pyrazole, which is known to induce hepatic cytochrome P4502A5 (CYP2A5) through posttranscriptional mechanisms, on the level of CYP2A5 in liver and extrahepatic tissues were examined in this study. Intraperitoneal administration of pyra
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
The metabolic activation of two known olfactory mucosal (OM) toxicants, acetaminophen (AP) and 2,6-dichlorobenzonitrile (DCBN), was examined with mouse liver and OM microsomes and purified, heterologously expressed mouse CYP2A5 and CYP2G1. In reconst