Zobrazeno 1 - 6
of 6
pro vyhledávání: '"T W, Lipinskas"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(8)
The effects of pyrazole, which is known to induce hepatic cytochrome P4502A5 (CYP2A5) through posttranscriptional mechanisms, on the level of CYP2A5 in liver and extrahepatic tissues were examined in this study. Intraperitoneal administration of pyra
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
The metabolic activation of two known olfactory mucosal (OM) toxicants, acetaminophen (AP) and 2,6-dichlorobenzonitrile (DCBN), was examined with mouse liver and OM microsomes and purified, heterologously expressed mouse CYP2A5 and CYP2G1. In reconst
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(8)
CYP2A10 and CYP2A11, which are abundant in olfactory microsomes from rabbits, are active in the metabolic activation of a number of nasal toxicants, such as hexamethylphosphoramide and N-nitrosodiethylamine. Previous immunohistochemical studies indic
Publikováno v:
Annals of the New York Academy of Sciences; 2000, Vol. 919 Issue 1, p148-170, 23p
Autor:
Genter, Mary Beth
Publikováno v:
Journal of Biochemical & Molecular Toxicology; 1998, Vol. 12 Issue 5, p305-314, 10p
Autor:
Woolf, Thomas F.
Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding f