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Cellular cytotoxicity mediated by isotype-switch variants of a monoclonal antibody to human neuroblastoma

Publikováno v: British Journal of Cancer

The biological property of an antibody is determined by its antigen binding characteristics and its isotype-related effector functions. We have established monoclonal antibodies of different isotypes by stepwise selection and cloning of the hybridoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3341b4152019daf751601575f1c47ae6
https://doi.org/10.1038/bjc.1991.329

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[Research from the Division of Immunology: production of nitric oxide (NO) by macrophages in ruminants]

Autor: T W, Jungi

Publikováno v: Schweizer Archiv fur Tierheilkunde. 142(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa5aa4c054a8ca48a3bc6f06a01d3de6
https://pubmed.ncbi.nlm.nih.gov/10850153

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Differences between B cell and macrophage transformation by the bovine parasite, Theileria annulata: a clonal approach

Autor: H, Sager, G, Bertoni, T W, Jungi

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(1)

Theileria annulata, a tick-transmitted protozoan parasite, infects and transforms cells of the hemopoietic system, particularly those of the B cell and monocyte/macrophage lineages. Here, the effect of infection/transformation on the resulting phenot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c254cb997b5b5a31002ab0eec7683cf7
https://pubmed.ncbi.nlm.nih.gov/9647241

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[Case presentation: bovine leukocyte adhesion deficiency (BLAD) in Switzerland]

Autor: M, Meylan, R, Abegg, H, Sager, T W, Jungi, J, Martig

Publikováno v: Schweizer Archiv fur Tierheilkunde. 139(6)

Bovine Leukocyte Adhesion Deficiency (BLAD) Syndrome is a lethal congenital immunodeficiency caused by the strong reduction in the expression of leukocyte integrins (beta 2 integrins) on the surface of leukocytes. Therefore, neutrophils from BLAD ani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e7ab664416625741a53350ae5c9ed3a
https://pubmed.ncbi.nlm.nih.gov/9411734

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Antibodies to human major histocompatibility complex products inhibit Fc gamma receptors types I and II

Autor: J. Neppert, T. W. Jungi

Publikováno v: Transfusion medicine (Oxford, England). 6(2)

We have analysed the effect of polyclonal and monoclonal antibodies of distinct IgG isotypes directed against products of the human major histocompatibility complex (MHC) on the function of Fc gamma receptors types I (Fc gamma RI) and II (Fc gamma RI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4640db4388709e11c0a8fd63cc66ca1
https://pubmed.ncbi.nlm.nih.gov/8809960

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Effect of human recombinant cytokines on the induction of macrophage procoagulant activity

Autor: I, Schwager, T W, Jungi

Publikováno v: Blood. 83(1)

A panel of human recombinant cytokines was tested for induction of procoagulant activity (PCA) in human monocyte-derived macrophages. Nonadherent culture conditions were used, and PCA was determined with whole cells rather than cell lysates. It was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f018ce63d0d51faf4438733f298b1bf2
https://pubmed.ncbi.nlm.nih.gov/8274733

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Human monocytes CD36 and CD16 are signaling molecules. Evidence from studies using antibody-induced chemiluminescence as a tool to probe signal transduction

Autor: C, Trezzini, T W, Jungi, M O, Spycher, F E, Maly, P, Rao

Publikováno v: Immunology. 71(1)

A panel of monoclonal antibodies (mAb) directed against human monocyte surface antigens was tested for their capacity to mediate signal transduction by measuring luminol-enhanced chemiluminescence (CL). The response patterns fell into three categorie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc9f522341e2da4dbf246bd0473d7290
https://pubmed.ncbi.nlm.nih.gov/1698715

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Plasma exchange and intravenous immunoglobulin infusion: antagonistic effects on mononuclear phagocyte functions with potential implications for therapy

Autor: T W, Jungi, U E, Nydegger

Publikováno v: Progress in clinical and biological research. 337

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1815eb803d38e0d0170d89560d32422
https://pubmed.ncbi.nlm.nih.gov/2191332

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Transfer of Immunity Against Listeria monocytogenes by T Cells Purified by a Positive Selection Technique

Autor: D. D. McGregor, E. D. Crum, R. G. Bell, T. W. Jungi

Publikováno v: Infection and Immunity. 22:209-218

Affinity columns prepared with rabbit antibody to the F(ab′) 2 fragment of rat immunoglobulin were used to separate rat thoracic duct lymphocytes into sub-populations that differ with respect to the density of their surface membrane immunoglobulin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ecea5749e0edf65f77e4fc4be6f67c
https://doi.org/10.1128/iai.22.1.209-218.1978

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