Zobrazeno 1 - 10
of 845
pro vyhledávání: '"T Virtanen"'
Autor:
Toni T. Lemmetyinen, Emma W. Viitala, Linnea Wartiovaara, Pekka Päivinen, Heikki T. Virtanen, Nalle Pentinmikko, Pekka Katajisto, Tomi P. Mäkelä, Timothy C. Wang, Jaan-Olle Andressoo, Saara Ollila
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111246- (2024)
Summary: Enteroendocrine cells (EECs) differentiate and mature to form functionally distinct populations upon migration along the intestinal crypt-villus axis, but how niche signals affect this process is poorly understood. Here, we identify expressi
Externí odkaz:
https://doaj.org/article/ea27196119484f11b10254daaf73c7e0
Autor:
Heikki T. Virtanen, Peyman Choopanian, L. Lauriina Porokuokka, Richard Forsgård, Daniel R. Garton, Soophie Olfat, Riitta Korpela, Mehdi Mirzaie, Jaan-Olle Andressoo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 6, Pp 101405- (2024)
Background & Aims: The size and function of the enteric nervous system (ENS) can vary substantially between individuals. Because ENS function is involved in the etiology of a growing number of common human diseases, understanding mechanisms that regu
Externí odkaz:
https://doaj.org/article/5f463772172d48d79f00ab45dff8d6ea
Autor:
L. Heiskanen, J.-P. Tuovinen, H. Vekuri, A. Räsänen, T. Virtanen, S. Juutinen, A. Lohila, J. Mikola, M. Aurela
Publikováno v:
Biogeosciences, Vol 20, Pp 545-572 (2023)
The subarctic landscape consists of a mosaic of forest, peatland, and aquatic ecosystems and their ecotones. The carbon (C) exchange between ecosystems and the atmosphere through carbon dioxide (CO2) and methane (CH4) fluxes varies spatially and temp
Externí odkaz:
https://doaj.org/article/80f02c027cf6474d9268777c442ec505
Autor:
S. Juutinen, M. Aurela, J.-P. Tuovinen, V. Ivakhov, M. Linkosalmi, A. Räsänen, T. Virtanen, J. Mikola, J. Nyman, E. Vähä, M. Loskutova, A. Makshtas, T. Laurila
Publikováno v:
Biogeosciences, Vol 19, Pp 3151-3167 (2022)
Arctic tundra is facing unprecedented warming, resulting in shifts in the vegetation, thaw regimes, and potentially in the ecosystem–atmosphere exchange of carbon (C). However, the estimates of regional carbon dioxide (CO2) and methane (CH4) budget
Externí odkaz:
https://doaj.org/article/2e4ff3a357864eb7a561546cc572eb12
Autor:
D. Olefeldt, M. Hovemyr, M. A. Kuhn, D. Bastviken, T. J. Bohn, J. Connolly, P. Crill, E. S. Euskirchen, S. A. Finkelstein, H. Genet, G. Grosse, L. I. Harris, L. Heffernan, M. Helbig, G. Hugelius, R. Hutchins, S. Juutinen, M. J. Lara, A. Malhotra, K. Manies, A. D. McGuire, S. M. Natali, J. A. O'Donnell, F.-J. W. Parmentier, A. Räsänen, C. Schädel, O. Sonnentag, M. Strack, S. E. Tank, C. Treat, R. K. Varner, T. Virtanen, R. K. Warren, J. D. Watts
Publikováno v:
Earth System Science Data, Vol 13, Pp 5127-5149 (2021)
Methane emissions from boreal and arctic wetlands, lakes, and rivers are expected to increase in response to warming and associated permafrost thaw. However, the lack of appropriate land cover datasets for scaling field-measured methane emissions to
Externí odkaz:
https://doaj.org/article/52b5da0f52cb481395efcc6ac1b6641a
Autor:
H. Brenot, N. Theys, L. Clarisse, J. van Gent, D. R. Hurtmans, S. Vandenbussche, N. Papagiannopoulos, L. Mona, T. Virtanen, A. Uppstu, M. Sofiev, L. Bugliaro, M. Vázquez-Navarro, P. Hedelt, M. M. Parks, S. Barsotti, M. Coltelli, W. Moreland, S. Scollo, G. Salerno, D. Arnold-Arias, M. Hirtl, T. Peltonen, J. Lahtinen, K. Sievers, F. Lipok, R. Rüfenacht, A. Haefele, M. Hervo, S. Wagenaar, W. Som de Cerff, J. de Laat, A. Apituley, P. Stammes, Q. Laffineur, A. Delcloo, R. Lennart, C.-H. Rokitansky, A. Vargas, M. Kerschbaum, C. Resch, R. Zopp, M. Plu, V.-H. Peuch, M. Van Roozendael, G. Wotawa
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 21, Pp 3367-3405 (2021)
The purpose of the EUNADICS-AV (European Natural Airborne Disaster Information and Coordination System for Aviation) prototype early warning system (EWS) is to develop the combined use of harmonised data products from satellite, ground-based and in s
Externí odkaz:
https://doaj.org/article/e4d686142ce94ec8a882cddb4e0e6429
Autor:
L. Heiskanen, J.-P. Tuovinen, A. Räsänen, T. Virtanen, S. Juutinen, A. Lohila, T. Penttilä, M. Linkosalmi, J. Mikola, T. Laurila, M. Aurela
Publikováno v:
Biogeosciences, Vol 18, Pp 873-896 (2021)
The patterned microtopography of subarctic mires generates a variety of environmental conditions, and carbon dioxide (CO2) and methane (CH4) dynamics vary spatially among different plant community types (PCTs). We studied the CO2 and CH4 exchange bet
Externí odkaz:
https://doaj.org/article/8e903e24f5be4ded9f3d0fb03434a083
Autor:
H. Zhang, E.-S. Tuittila, A. Korrensalo, A. Räsänen, T. Virtanen, M. Aurela, T. Penttilä, T. Laurila, S. Gerin, V. Lindholm, A. Lohila
Publikováno v:
Biogeosciences, Vol 17, Pp 6247-6270 (2020)
Northern peatlands are projected to be crucial in future atmospheric methane (CH4) budgets and have a positive feedback on global warming. Fens receive nutrients from catchments via inflowing water and are more sensitive than bogs to variations in th
Externí odkaz:
https://doaj.org/article/fe1b4427733b407680cae8da8a2b80bf
Autor:
Anniina T. Virtanen, Teemu Haikarainen, Parthasarathy Sampathkumar, Maaria Palmroth, Sanna Liukkonen, Jianping Liu, Natalia Nekhotiaeva, Stevan R. Hubbard, Olli Silvennoinen
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 75 (2023)
Hyperactive mutation V617F in the JAK2 regulatory pseudokinase domain (JH2) is prevalent in patients with myeloproliferative neoplasms. Here, we identified novel small molecules that target JH2 of JAK2 V617F and characterized binding via biochemical
Externí odkaz:
https://doaj.org/article/6cfdba99ff324992a07f46b8c564e944
Autor:
L. Lauriina Porokuokka, Heikki T. Virtanen, Jere Lindén, Yulia Sidorova, Tatiana Danilova, Maria Lindahl, Mart Saarma, Jaan-Olle Andressoo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 3, Pp 655-678 (2019)
Background & Aims: RET, the receptor for the glial cell line–derived neurotrophic factor (GDNF) family ligands, is the most frequently mutated gene in congenital aganglionic megacolon or Hirschsprung’s disease (HSCR). The leading cause of mortali
Externí odkaz:
https://doaj.org/article/4093d27634394fabbd2090d68e2d8c5b