Zobrazeno 1 - 10
of 20
pro vyhledávání: '"T V, Gupalova"'
Publikováno v:
Эпидемиология и вакцинопрофилактика, Vol 22, Iss 4, Pp 4-11 (2023)
The mucosal membranes of the human body play a crucial role in the development, maintenance, and regulation of barrier functions and immune homeostasis, representing an integral component of the overall immune system. Mucosal vaccines elicit immune p
Externí odkaz:
https://doaj.org/article/39c2a79b010b458fb976c152a36bcae0
Publikováno v:
Russian Journal for Personalized Medicine. 3:64-71
The current pandemic caused by the SARS-Cov-2 virus has significantly influenced the emergence of new injectable vaccines that provide a predominantly specific IgG response. However, it is generally accepted that protection against pathogens at the m
Autor:
G. F. Leontieva, T. A. Kramskaya, K. B. Grabovskaya, T. V. Gupalova, A. V. Dmitriev, A. N. Suvorov
Publikováno v:
Russian Journal for Personalized Medicine. 2:64-77
The use of recombinant proteins as vaccine preparations is limited by their weak immunogenicity, which can be enhanced by the use of adjuvants, the development of which is an important and urgent problem of modern vaccinology. Significantly, adjuvant
Autor:
A. N. Suvorov, G. F. Leontyeva, L. F. Meringova, K. B. Grabovskaya, T. V. Gupalova, E. I. Vorobyeva, A. S. Simbirtsev, A. A. Kolobov, Artem A. Totolian
Publikováno v:
Медицинская иммунология, Vol 10, Iss 2-3, Pp 215-222 (2014)
Abstract. Design of an effective and safe vaccine against pathogenic streptococci is still on the agenda, in spite of numerous attempts in this area undertaken by different laboratories. In order to improve immunogenicity of recombinant vaccine prepa
Externí odkaz:
https://doaj.org/article/5e2909d8e03f45c393bda86ef4319b67
Autor:
L. A. Burova, P. V. Pigarevsky, E. A. Gavrilova, V. G. Seliverstova, K. Schalen, Artem A. Totolyan, T. V. Gupalova
Publikováno v:
Медицинская иммунология, Vol 14, Iss 4-5, Pp 383-390 (2014)
Abstract. Pathogenesis of acute post-streptococcal glomerulonephritis (APSGN), a major complication of group A streptococcal (GAS) throat or skin disease, remains unclear. Over years, various theories were based on distinct streptococcal extracellula
Externí odkaz:
https://doaj.org/article/8101022437ba46e391df35c633d9be65
Autor:
E A Bormotova, T V Gupalova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 165:373-377
Protein G is present in group G streptococcus strain (G4223); the IgG-binding part of this protein contains three IgG-binding domains and binds human IgG with very high activity. We obtained two recombinant polypeptides G4223 and G14223 with high IgG
Publikováno v:
Сахарный диабет, Vol 5, Iss 4, Pp 40-42 (2002)
Поражение почек при сахарном диабете (СД) типа 2 развивается у 30-60% больных. В 5-10% случаев диабетическая нефропатия (ДН) заканчивается терм
Externí odkaz:
https://doaj.org/article/733819a601b74443876ed4edcf7105b3
Autor:
T. V. Gupalova, E. A. Bormotova
Publikováno v:
Bulletin of experimental biology and medicine. 169(4)
Many streptococcal strains bind to two main human blood plasma proteins: IgG and human serum albumin (HSA). Protein G expressed in group C and G streptococci has specific binding regions for these proteins. Protein G in group G streptococcal strains
Autor:
E A, Bormotova, T V, Gupalova
Publikováno v:
Klinicheskaia laboratornaia diagnostika. 61(8)
The diabetes mellitus and arterial hypertension are among the most significant pathologies conditioning disorder of excretion of protein with urine. These very diseases are mostly dangerous for kidneys. Therefore, important significance has the searc
Autor:
T. V. Gupalova, E. A. Bormotova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 162:66-70
Surface proteins of many bacterial species interact with human serum albumin (HSA) via a special region of amino acid sequence termed GA module. For instance, surface peptostreptococcal albumin-binding protein of anaerobic bacteria Peptostreptococcus