Zobrazeno 1 - 10
of 33
pro vyhledávání: '"T Truschel"'
Autor:
Chang Liu, Tiffany Tate, Ekatherina Batourina, Steven T. Truschel, Steven Potter, Mike Adam, Tina Xiang, Martin Picard, Maia Reiley, Kerry Schneider, Manuel Tamargo, Chao Lu, Xiao Chen, Jing He, Hyunwoo Kim, Cathy Lee Mendelsohn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The nuclear receptor Pparg regulates urothelial differentiation in vitro but its role in healthy urothelium is unclear. Here, the authors show that PPAR gamma mediates urothelial development during both homeostasis (via mitochondrial function) and fo
Externí odkaz:
https://doaj.org/article/303531835cbf4da28f7e0d26a90b094e
Autor:
Steven T Truschel, Dennis R Clayton, Jonathan M Beckel, Jonathan G Yabes, Yi Yao, Amanda Wolf-Johnston, Lori A Birder, Gerard Apodaca
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198817 (2018)
Lysosomal dysfunction is associated with a number of age-related pathologies that affect all organ systems. While much research has focused on neurodegenerative diseases and aging-induced changes in neurons, much less is known about the impact that a
Externí odkaz:
https://doaj.org/article/b24393ea745b48c1b626f706b41e29d9
Autor:
C Lipps, A Yogeswaran, J McNamara, J Wilhelm, T Truschel, M Aslam, S Reischauer, S Voss, T Keller, O Doerr, H Nef, C W Hamm, S Sadayappan, C Troidl
Publikováno v:
European Heart Journal. 42
Background Cardiac myosin binding protein-C is a protein expressed in the myosin thick filament backbone that was recently described as a novel cardiac biomarker. Its N-terminal region, C0-C1f, is released within the first minutes of ischemia and pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a440609339487e69bff8054ead6c1b3d
https://doi.org/10.1093/eurheartj/ehab724.3246
https://doi.org/10.1093/eurheartj/ehab724.3246
Akademický článek
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Autor:
Thomas M. Kessler, Gerard Apodaca, Anthony Kanai, Lori A. Birder, Aura Kullmann, Amanda Wolf-Johnston, Andrew M. Lynn, Bronagh McDonnell, Steven T. Truschel
Publikováno v:
Neurourol Urodyn
Aim To characterize the effects of acute spinal cord injury (SCI) on mitochondrial morphology and function in bladder urothelium and to test the therapeutic efficacy of early treatment with the mitochondrially targeted antioxidant, MitoTempo. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145f156564950148f89003a26a38733e
https://europepmc.org/articles/PMC7528977/
https://europepmc.org/articles/PMC7528977/
Autor:
Amanda Wolf-Johnston, Anthony Kanai, Bronagh McDonnell, Lori A. Birder, Steven T. Truschel, Aura Kullmann, Gerard Apodaca
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Spinal cord injury (SCI) is associated with significant changes in bladder function. We have previously shown that early after SCI there are morphological changes to the...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09104d506f99278b09ee6b70fbb0213d
https://doi.org/10.1097/01.ju.0000555472.42667.6e
https://doi.org/10.1097/01.ju.0000555472.42667.6e
Autor:
Martin Picard, Xiao Chen, Maia Reiley, Jing He, S. Steven Potter, Kerry Schneider, Cathy Mendelsohn, Manuel A. Tamargo, Hyunwoo Kim, Tiffany Tate, Mike Adam, Chao Lu, Chang Liu, Ekatherina Batourina, Steven T. Truschel, Tina Xiang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The urothelium is an epithelial barrier lining the bladder that protects against infection, fluid exchange and damage from toxins. The nuclear receptor Pparg promotes urothelial differentiation in vitro, and Pparg mutations are associated with bladde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4980b5a0862fc7c9452306a7cd46c9
https://pubmed.ncbi.nlm.nih.gov/31597917
https://pubmed.ncbi.nlm.nih.gov/31597917
Autor:
Gerard Apodaca, Dennis R. Clayton, Amanda Wolf-Johnston, Lori A. Birder, Steven T. Truschel, Yi Yao, Jonathan M. Beckel, Jonathan G. Yabes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0198817 (2018)
PLoS ONE, Vol 13, Iss 6, p e0198817 (2018)
Lysosomal dysfunction is associated with a number of age-related pathologies that affect all organ systems. While much research has focused on neurodegenerative diseases and aging-induced changes in neurons, much less is known about the impact that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de5346096d54bdd0e25022872e89554
https://doi.org/10.1371/journal.pone.0198817
https://doi.org/10.1371/journal.pone.0198817
Autor:
David C. Cowan, Subba Rao Gangi Setty, Steven T. Truschel, Sara D. Sackett, Danièle Tenza, Graça Raposo, Michael S. Marks, Penelope C. Thomas, Sabrina Simoes, Alexander C. Theos, Dawn C. Harper, Kathryn E. Herman
Publikováno v:
Traffic. 10:1318-1336
Melanosomes are lysosome-related organelles that coexist with lysosomes within melanocytes. The pathways by which melanosomal proteins are diverted from endocytic organelles toward melanosomes are incompletely defined. In melanocytes from mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba7c5432deec9d0778aac1bf27a6047
https://doi.org/10.1111/j.1600-0854.2009.00955.x
https://doi.org/10.1111/j.1600-0854.2009.00955.x
Autor:
Danièle Tenza, Steven T. Truschel, Dorothy C. Bennett, M. Lynn Lamoreux, Graça Raposo, Evelyn Chou, Alexander C. Theos, Marta Starcevic, Santiago M. Di Pietro, Subba Rao Gangi Setty, Elena V. Sviderskaya, Michael S. Marks, Esteban C. Dell'Angelica
Publikováno v:
Molecular Biology of the Cell
Hermansky-Pudlak syndrome (HPS) is a genetic disorder characterized by defects in the formation and function of lysosome-related organelles such as melanosomes. HPS in humans or mice is caused by mutations in any of 15 genes, five of which encode sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c267b753fc5cb8ae28b18ce9ea50c1
https://doi.org/10.1091/mbc.e06-12-1066
https://doi.org/10.1091/mbc.e06-12-1066