Differentiation of patient-specific void urine-derived human induced pluripotent stem cells to fibroblasts and skeletal muscle myocytes

Autor: M. Kibschull, T. T. N. Nguyen, T. Chow, M. Alarab, S. J. Lye, I. Rogers, O. Shynlova

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract Cell-based therapy is a major focus for treatment of stress urinary incontinence (SUI). However, derivation of primary cells requires tissue biopsies, which often have adverse effects on patients. A recent study used human induced pluripoten

Externí odkaz: https://doaj.org/article/42b36d8ec1e746929b115f67a5807e64

Pegylated interferon may be considered in chronic viral hepatitis E resistant to ribavirin in kidney transplant recipients

Autor: I. Ollivier-Hourmand, L. Lebedel, A. Lecouf, M. Allaire, T. T. N. Nguyen, C. Lier, T. Dao

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-5 (2020)

Abstract Background Hepatitis E virus (HEV) may be resistant to immunosuppression reduction and ribavirin treatment in kidney transplant recipients because of mutant strains and severe side effects of ribavirin which conduct to dose reduction. Sofosb

Externí odkaz: https://doaj.org/article/b4b18d63b4b7467584a418690f5c360d

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Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid

Autor: Kasper D. Rand, Anne-Marie Jacobsen, Line Olsen, Tam T. T. N. Nguyen, Jens Rose Fogh

Publikováno v: Analytical and Bioanalytical Chemistry
Fogh, J R, Jacobsen, A-M, Nguyen, T T T N, Rand, K D & Olsen, L R 2020, ' Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid ', Analytical and Bioanalytical Chemistry, vol. 412, pp. 1653-1661 . https://doi.org/10.1007/s00216-020-02403-3

As quantitative analysis of biotherapeutics in cerebrospinal fluid (CSF) with LC-MS becomes increasingly widespread, there is a need for method developments towards higher sensitivity. By using artificial CSF (aCSF) in the development phase, the cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c386c8a67b1b16484a31b1ecf76d2d4
http://europepmc.org/articles/PMC7026242