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Publikováno v:
Toxicology and Applied Pharmacology. 415:115439
Non-genotoxic carcinogens (NGCs) are known to cause perturbations in DNA methylation, which can be an early event leading to changes in gene expression and the onset of carcinogenicity. Phenobarbital (PB) has been shown to alter liver DNA methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f8aa32832551a21a018f901129bffc
https://doi.org/10.1016/j.taap.2021.115439
https://doi.org/10.1016/j.taap.2021.115439
Autor:
Wayne R. Buck, V. Devanarayan, Eric A. G. Blomme, J. Maher, Bruce E. LeRoy, T. Sharapova, Michael J. Liguori
Publikováno v:
Veterinary pathology. 53(1)
MicroRNAs are short noncoding RNAs involved in regulation of gene expression. Certain microRNAs, including miR-122, seem to have ideal properties as biomarkers due to good stability, high tissue specificity, and ease of detection across multiple spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8fb0c0e145edf252b2a82bc7f7fcc5
https://pubmed.ncbi.nlm.nih.gov/26123229
https://pubmed.ncbi.nlm.nih.gov/26123229
Autor:
Yury Verlinsky, Mohammed Taranissi, Svetlana Rechitsky, Anver Kuliev, Randy Morris, T Sharapova
Publikováno v:
Obstetrical & Gynecological Survey. 59:703-705
When couples reject termination of a genetically affected pregnancy that has been identified by traditional prenatal diagnosis, preimplantation genetic diagnosis (PGD) is an alternative option. PGD, based on ovarian stimulation and in vitro fertiliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb160e8343ed3808354516e9b3cf758e
https://doi.org/10.1097/01.ogx.0000141209.41960.8b
https://doi.org/10.1097/01.ogx.0000141209.41960.8b
Autor:
K. Schaefer, E. Blomme, T. Sharapova, K. Bodié, Mohan S. Rao, P. Germann, R. Geil, K. Hempel, Wayne R. Buck
Publikováno v:
Toxicology Letters. 258:S79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0926b442edf57aff7738bb410f84c638
https://doi.org/10.1016/j.toxlet.2016.06.1365
https://doi.org/10.1016/j.toxlet.2016.06.1365
Autor:
Oleg Verlinsky, Anver Kuliev, I Barsky, K Laziuk, T Sharapova, Svetlana Rechitsky, Ilan Tur-Kaspa, Yury Verlinsky
Publikováno v:
Reproductive biomedicine online. 14(2)
Preimplantation genetic diagnosis (PGD) has become an established procedure for the detection of single gene disorders, and has recently been performed together with human leukocyte antigen (HLA) typing for couples with children affected by genetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80bd577fcc8a722f26f7116b931516a
https://pubmed.ncbi.nlm.nih.gov/17298726
https://pubmed.ncbi.nlm.nih.gov/17298726
Autor:
Svetlana Rechitsky, Oleg Verlinsky, Yury Verlinsky, Seckin Ozen, T Sharapova, I Barsky, K Laziuk, Anver Kuliev, Ilan Tur-Kaspa
Publikováno v:
Reproductive biomedicine online. 12(1)
Preimplantation HLA typing has been introduced for the treatment of affected siblings, requiring HLA-identical stem cell transplantation. This was applied either in combination with preimplantation genetic diagnosis (PGD) to ensure that the preselect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46af470126d5aea8c7d19e6b408a4717
https://pubmed.ncbi.nlm.nih.gov/16454942
https://pubmed.ncbi.nlm.nih.gov/16454942
Autor:
Anna Chistokhina, Yury Verlinsky, K. Lederer, T Sharapova, Oleg Verlinsky, Svetlana Rechitsky, Brian Kaplan, Anver Kuliev, Michael J. Levy, Christina Masciangelo
Publikováno v:
Reproductive biomedicine online. 4(3)
Preimplantation genetic diagnosis (PGD) has recently been performed for inherited cancer predisposition determined by p53 tumour suppressor gene mutations, suggesting the usefulness of PGD for late onset disorders with genetic predisposition, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2066a8b386507ce95abf1136d9dd670
https://pubmed.ncbi.nlm.nih.gov/12709270
https://pubmed.ncbi.nlm.nih.gov/12709270
Autor:
Christina Masciangelo, Oleg Verlinsky, Randy Morris, T Sharapova, Yury Verlinsky, Svetlana Rechitsky, Anver Kuliev, Seckin Ozen
Publikováno v:
The New England journal of medicine. 348(15)
Mutations in the sonic hedgehog gene have been linked to holoprosencephaly. Mosaicism for the sonic hedgehog mutation was identified by single-sperm testing in a man who had fathered two affected children. Genomic DNA was normal in both parents on sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b4ee9ab945cdf8cf9da873a07f29b4
https://pubmed.ncbi.nlm.nih.gov/12686701
https://pubmed.ncbi.nlm.nih.gov/12686701
Autor:
Seckin Ozen, Yury Verlinsky, Christina Masciangelo, Anna Chistokhina, T Sharapova, Anver Kuliev, Svetlana Rechitsky, Oleg Verlinsky
Publikováno v:
Reproductive biomedicine online. 5(2)
Preimplantation genetic diagnosis (PGD) has recently been offered for couples with an inherited predisposition for late onset disorders. This paper presents the results of PGD for a group of couples at risk for producing children with cancer predispo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7124d3ff83ea618603fb7a15d2b56eff
https://pubmed.ncbi.nlm.nih.gov/12419039
https://pubmed.ncbi.nlm.nih.gov/12419039