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Publikováno v:
Chemistrybiology. 8(5)
Using fixed receptor sites derived from high-resolution crystal structures in structure-based drug design does not properly account for ligand-induced enzyme conformational change and imparts a bias into the discovery and design of novel ligands. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4934d0bd8cd7033542df58ecd1ca7c1f
https://pubmed.ncbi.nlm.nih.gov/11358692
https://pubmed.ncbi.nlm.nih.gov/11358692
