Výsledky vyhledávání - "T S, Oretskaia"

[2'-aldehyde oligonucleotides: synthesis and use for affinity modification of DNA-recognizing proteins]

Autor: E A, Khomiakova, E V, Kazanova, E M, Zubin, E A, Kubareva, N V, Molochkov, E M, Riazanova, T S, Oretskaia

Publikováno v: Bioorganicheskaia khimiia. 36(3)

Oligonucleotides with 1,2-diol grouping were prepared from 2'-O-[2-(2,3-dihydroxypropyl)amino-2-oxo-ethyl]uridine 3'-phosphoramidite. The thermal stability of modified DNA duplexes and their ability to form complexes with the p50 subunit of the NF-ka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::460fe52d59142f7f0867815187e85da4
https://pubmed.ncbi.nlm.nih.gov/20644589

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[New derivatives of azobenzene for the directed modification of proteins]

Autor: Le Tkhi, Khien, B, Shirling, A Iu, Riazanova, T S, Zatsepin, E M, Volkov, E A, Kubareva, T I, Velichko, A, Pingoud, T S, Oretskaia

Publikováno v: Bioorganicheskaia khimiia. 35(5)

Derivatives of azobenzene which contained a maleimide group in one of the benzene rings (for binding to a protein cysteine residue) and maleimide, hydroxyl, or carboxyl substitutes in another benzene ring were synthesized. The reactivity of these com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3249db46c06735795871f33a5568eba6
https://pubmed.ncbi.nlm.nih.gov/19915638

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[Covalent binding of Cys142 from SsoII methyltransferase with DNA duplexes, containing a phosphoryldisulfide internucleotide group]

Autor: O V, Vorob'eva, A S, Romanenkov, V G, Metelev, A S, Kariagina, N V, Lavrova, T S, Oretskaia, E A, Kubareva

Publikováno v: Molekuliarnaia biologiia. 37(5)

DNA duplexes containing a single phosphoryldisulfide link in place of the natural internucleotide phosphodiester bond were employed in affinity modification of Cys142 in cytosine-C5 DNA methyltransferase SsoII (M.SsoII). The possibility of duplex-M.S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2b92b2980733b606969d420f96c821f
https://pubmed.ncbi.nlm.nih.gov/14593929

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[Solid phase synthesis and chromatographic characteristics of nucleophilic agents conjugated with oligonucleotides containing 5'-terminal carboxyl group]

Autor: A V, Kachalova, V N, Tashlitskiĭ, D A, Stetsenko, E A, Romanova, M J, Gait, T S, Oretskaia

Publikováno v: Bioorganicheskaia khimiia. 29(3)

Conjugates of amines or short peptides with oligonucleotides containing 5'-terminal carboxyl group were prepared by solid phase chemical synthesis. A correlation between the physicochemical parameters and retention times of the synthesized conjugates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e523b091c03edb0a9034147c6eedc5bd
https://pubmed.ncbi.nlm.nih.gov/12845806

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[DNA duplexes containing 2'-deoxy-2'-iodoacetamidouridine as reagents for affinity modification of proteins]

Autor: O A, Borisova, A S, Romanenkov, V G, Metelev, E A, Kubareva, E M, Zubin, M A, Timchenko, T S, Oretskaia

Publikováno v: Molekuliarnaia biologiia. 37(3)

DNA duplexes containing the iodoacetamido group at position 2' of the ribose moiety were proposed for affinity modification of Cys in DNA-binding proteins. Reactive DNA derivatives were obtained with iodoacetic anhydride and synthetic oligodeoxyribon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14a26951b2a36464b42ec8dc26958257
https://pubmed.ncbi.nlm.nih.gov/12815962

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[Synthesis and properties of oligodeoxyribonucleotids with mono- and diphosphoryldisulfide internucleotide groupings]

Autor: V G, Metelev, E A, Kubareva, E A, Romanova, T S, Oretskaia

Publikováno v: Bioorganicheskaia khimiia. 29(1)

The synthesis of oligodeoxyribonucleotides bearing mono- and diphosphoryldisulfide internucleotide links was optimized. Oligonucleotide 3'-thiophosphorothioates were modified using the thiophosphoryl-disulfide exchange with preactivated 5'-deoxy-5'-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b93b18ac88f6463b728866329cbbb3f8
https://pubmed.ncbi.nlm.nih.gov/12658993

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[An analysis of methyltransferase SsoII-DNA contacts in the enzyme-substrate complex]

Autor: O V, Vorob'eva, A S, Kariagina, E M, Volkov, M B, Viriasov, T S, Oretskaia, E A, Kubareva

Publikováno v: Bioorganicheskaia khimiia. 28(5)

The functional groups of the DNA methylation site that are involved in the DNA interaction with methyltransferase SsoII at the recognition stage were identified. The contacts in the enzyme-substrate complex were analyzed in the presence of S-adenosyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc20037279fde409112c88e6e19a910d
https://pubmed.ncbi.nlm.nih.gov/12408024

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[Crosslinking of transcription factor NF-kappaB with a DNA ligand bearing the 2'-aldehyde group]

Autor: D V, Turutin, T S, Zatsepin, M A, Timchenko, E A, Kubareva, T S, Oretskaia

Publikováno v: Molekuliarnaia biologiia. 36(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e71d814e85d9700055e0e424d2224e2b
https://pubmed.ncbi.nlm.nih.gov/12391852

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[Synthesis of oligodeoxyribonucleotides containing oleylamine moieties]

Autor: S Iu, Andreev, S I, Antsypovich, E M, Volkov, E A, Romanova, T, Hianik, T S, Oretskaia

Publikováno v: Bioorganicheskaia khimiia. 27(3)

A method for directional introduction of oleylamine residues to any position of oligodeoxyribonucleotides during their automated synthesis was developed. The presence of oleylamine residues in 3'- or 5'-terminal nucleotides was shown to have no effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc56533aa8388d0be1811808b029e78b
https://pubmed.ncbi.nlm.nih.gov/11443944

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