Zobrazeno 1 - 10 of 76 pro vyhledávání: '"T S, Herman"'
1
Glutathione S-transferase Alpha 4 Induction by Activator Protein 1 in Colorectal Cancer
Autor: Y Yang, Xingmin Wang, T S Herman, Mark M. Huycke
Publikováno v: Oncogene
Glutathione S-transferase alpha 4 (GSTA4) is a phase II detoxifying enzyme that metabolizes electrophiles and carcinogens including 4-hydroxy-2-nonenal (4-HNE), an endogenous carcinogen that contributes to colorectal carcinogenesis. In this study, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e751d344a83457b857d1c57a4c85fd75
https://europepmc.org/articles/PMC9619338/
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2
Post-translational modification of I-kappa B alpha activates NF-κB in human monocytes exposed to 56Fe ions
Autor: M. L. Meltz, Mohan Natarajan, T. S. Herman, Natarajan Aravindan
Publikováno v: Europe PubMed Central
The objective of this study was to investigate whether heavy ion (56Fe) radiation exposure activates one of the key transcriptional regulators, nuclear factor-kappa B (NF-kappa B), in normal human monocytes (Mono Mac 6 cells: MM6). The study revealed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06618dc708e7dc7e410ffbed68dfd9d
https://doi.org/10.1007/s00411-002-0143-x
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3
Summary of studies adding systemic chemotherapy to local hyperthermia and radiation
Autor: T. S. Herman, Beverly A. Teicher
Publikováno v: International Journal of Hyperthermia. 10:443-449
The Joint Center-MIT group sought to maximize the efficacy of hyperthermia plus radiation by adding systemic anticancer drugs chosen in the laboratory. After extensive laboratory investigations utilizing primarily the FSaIIC murine fibrosarcoma, we d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32327d8b69bfd3a051016a5bdbe2df75
https://doi.org/10.3109/02656739409010290
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4
Once-daily fosinopril in the treatment of hypertension
Autor: T M Nolen, P Wolfson, D G Wombolt, T S Herman, K L Duchin, R D Gore, P S Nichola, R S Michaels, Randall M. Zusman, R J Anderson
Publikováno v: Hypertension. 17:636-642
This multicenter, dose-ranging study evaluated the antihypertensive effectiveness of once-daily administration of fosinopril sodium in 220 patients with supine diastolic blood pressure of 95-115 mm Hg. After a 4-week placebo period, patients were ran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f180a9534050c23473b723c7c0f9659
https://doi.org/10.1161/01.hyp.17.5.636
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5
MODULATION OF [CIS-DIAMINEDICHLOROPLATINUM(II) HYPERTHERMIA] THERAPY BY INHIBITORS OF ARACHIDONIC-ACID METABOLISM
Autor: Sa Holden, T. S. Herman, B. A. Teicher, David Northey
Publikováno v: International Journal of Oncology.
Previous studies have shown that hyperthermia is an effective modulator of cis-diamminedichloroplatinum(II) (CDDP) cytotoxicity. We have examined the potential of inhibitors of the arachidonic acid metabolism to increase the antitumor activity of CDD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf91e82c25ca4ff5e6a10c75d3f5bf54
https://doi.org/10.3892/ijo.4.1.17
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6
A carbonic anhydrase inhibitor as a potential modulator of cancer therapies
Autor: B A, Teicher, S D, Liu, J T, Liu, S A, Holden, T S, Herman
Publikováno v: Anticancer research. 13(5A)
Since several anticancer drugs are known to become more cytotoxic to cells in an acidic milieu, we have attempted to utilize the carbonic anhydrase inhibitor, Acetazolamide, to acidify the blood and tumor of C3H mice bearing the FSaIIC fibrosarcoma i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::999a1c823fdd0f65492d546306b39704
https://pubmed.ncbi.nlm.nih.gov/8239534
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7
Response of subpopulations of the FSall C fibrosarcoma to low dose x-rays and various potential enhancing agents
Autor: J, Tanaka, S A, Holden, T S, Herman, B A, Teicher
Publikováno v: Anticancer research. 12(3)
The effectiveness of various oxygen carrying treatments in sensitizing subpopulations of the FSallC fibrosarcoma to low doses of radiation was assessed, and compared with survivals obtained with the same cells after in vivo irradiation under normally
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bba04991b4464f72544c69929074105
https://pubmed.ncbi.nlm.nih.gov/1622113
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8
Effect of hypoxia and acidosis on the cytotoxicity of mitoxantrone, bisantrene and amsacrine and their platinum complexes at normal and hyperthermic temperatures
Autor: T S, Herman, B A, Teicher, A, Varshney, V, Khandekar, T, Brann
Publikováno v: Anticancer research. 12(3)
In an effort to synthesize drugs which would become much more cytotoxic at clinically achievable hyperthermic temperatures, complexes of the tetrachloro-platinum(II) dianion were made with two anthracene dye derivatives, MITOX and BISANT, and the acr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93cf9a5160e9d886e70d6ebc8e1244cc
https://pubmed.ncbi.nlm.nih.gov/1622142
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