Zobrazeno 1 - 10
of 100
pro vyhledávání: '"T S, Glushchenko"'
Publikováno v:
Neuroscience and Behavioral Physiology. 50:388-391
Objective. To study changes in the level of DNA methylation in rat neocortex and hippocampus cells on exposure to different hypobaric hypoxia regimes. Materials and methods. Studies were performed on 24 adult male Wistar rats (180–200 g). Animals w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99e4ae2078741b143f46767c6957c9b2
https://doi.org/10.1007/s11055-020-00910-5
https://doi.org/10.1007/s11055-020-00910-5
Publikováno v:
Neuroscience and Behavioral Physiology. 49:1022-1026
Objective. To study the effects of severe hypobaric hypoxia followed by sessions of moderate hypobaric hypoxia using a postconditioning regime (PostC) with neuroprotective properties on the level of acetylation of histone H3 in rat hippocampal neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7580e4936d19afe13748af988544199b
https://doi.org/10.1007/s11055-019-00832-x
https://doi.org/10.1007/s11055-019-00832-x
Autor:
O. V. Vetrovoy, R. M. Aramisova, T. S. Glushchenko, E. I. Tyul’kova, K. V. Sarieva, M. O. Samoilov
Publikováno v:
Neurochemical Journal. 12:241-247
Recent studies imply that epigenetic mechanisms may play a key role in the pathogenesis of severe neurological diseases. We have previously shown that acetylation of histone H3 at Lys 24 (H3acK24) is involved in the formation of acute adaptive respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d598e159ffd82390569edd02b0ea510
https://doi.org/10.1134/s1819712418030157
https://doi.org/10.1134/s1819712418030157
Publikováno v:
Neurochemical Journal. 12:23-32
It is known that mild hypobaric hypoxia preconditioning may prevent brain damage induced by ischemic stroke and other forms of hypoxia. Activation of the antioxidant systems is one of the key molecular mechanisms that protect cells from oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad17b2a68bfb7345509e8e38094e7db1
https://doi.org/10.1134/s1819712418010142
https://doi.org/10.1134/s1819712418010142
Publikováno v:
Neurochemical Journal. 11:309-314
Hypoxic stress has a considerable effect on fetal development and may lead to irreversible longterm developmental disorders of the brain, increasing the risk of neurological complications. Modern research shows that epigenetic mechanisms may play a k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811582e735621e9faad38a65eee9f28f
https://doi.org/10.1134/s1819712417040109
https://doi.org/10.1134/s1819712417040109
Publikováno v:
Neurochemical Journal. 11:221-228
Using the quantitative immunohistochemical method, we analyzed changes in the number of cells that were immunopositive for methylated forms of histone H3 at lysine 4 (H3K4me2,3) and lysine 9 (H3K9me2) in the parietal neocortex and hippocampus (the С
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77cff78ca9f9f4ce1806efcf7a129e35
https://doi.org/10.1134/s1819712417020106
https://doi.org/10.1134/s1819712417020106
Publikováno v:
Bulletin of Experimental Biology and Medicine. 162:722-725
We studied the effects of different modes of hypobaric hypoxia on the content of epigenetic factors acH3K24, meH3K9, and meDNA modulating conformational characteristics of chromatin and gene expression in neurons of associative complex of rat parieta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f9cbc833372d31e51d8dbada9ea529
https://doi.org/10.1007/s10517-017-3697-y
https://doi.org/10.1007/s10517-017-3697-y
Publikováno v:
Neuroscience and Behavioral Physiology. 46:868-872
Studies on five groups of rats (six animals per group) addressed changes in neurons in hippocampal fields CA1 and CA4 seven days after severe hypobaric hypoxia (180 mmHg, 3 h) using different numbers (1, 3, or 6) of sessions of preconditioning (PC) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d38561546ff986c50c74c0fb6b41f63
https://doi.org/10.1007/s11055-016-0324-8
https://doi.org/10.1007/s11055-016-0324-8
Publikováno v:
Bulletin of Experimental Biology and Medicine. 160:510-513
The expression of neurogenesis marker – NeuroD2 transcription factor – in the hippocampal dentate gyrus was studied in rats exposed to severe destructive hypoxia, a single or three episodes of moderate hypobaric hypoxia, preconditioned severe hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c56568c313da1d7863fc706aa4e0e54
https://doi.org/10.1007/s10517-016-3209-5
https://doi.org/10.1007/s10517-016-3209-5
Publikováno v:
Neurochemical Journal. 9:299-305
Using the immunohistochemical method, we studied changes in the expression of the hypoxia-inducible factor (HIF-1α) in the neocortex and hippocampus of rats after moderate preconditioning (MH), severe (SH) hypobaric hypoxia, and their combined actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d45f4da9ab6a944703571945e9e7a0c
https://doi.org/10.1134/s1819712415040145
https://doi.org/10.1134/s1819712415040145