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Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes

Autor: G S, Akerman, W H, Tolleson, K L, Brown, L L, Zyzak, E, Mourateva, T S, Engin, A, Basaraba, A L, Coker, K E, Creek, L, Pirisi

Publikováno v: Cancer research. 61(9)

Epidermal growth factor receptor (EGFR) levels are dramatically increased in human keratinocytes (HKc) immortalized with full-length human papillomavirus type 16 (HPV16) DNA (HKc/HPV16), but increases in EGFR levels actually precede immortalization.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84801d57516d638eea8747563bca771c
https://pubmed.ncbi.nlm.nih.gov/11325860

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