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pro vyhledávání: '"T S, Angeles"'
Autor:
A M, Camoratto, J P, Jani, T S, Angeles, A C, Maroney, C Y, Sanders, C, Murakata, N T, Neff, J L, Vaught, J T, Isaacs, C A, Dionne
Publikováno v:
International journal of cancer. 72(4)
The present report describes the in vitro and in vivo profile of CEP-751, a novel receptor tyrosine kinase inhibitor. CEP-751 at 100 nM inhibits the receptor tyrosine kinase activity of the neurotrophin receptors trkA, trkB and trkC. CEP-751 has no e
Publikováno v:
Methods in enzymology. 241
Despite the current plethora of structural data of HIV-1 protease and the availability of potent inhibitors, whose structures are based in part on the presumed mechanism of action of this enzyme, our actual understanding of its chemical mechanism has