Zobrazeno 1 - 10
of 16
pro vyhledávání: '"T R Korfhagen"'
Publikováno v:
The Journal of Immunology. 158:4336-4340
To determine the role of surfactant protein A (SP-A) in host defense, the murine SP-A locus was targeted by homologous recombination to produce mice lacking SP-A. SP-A -/- and control mice were infected with group B streptococcus (GBS) by intratrache
Publikováno v:
Journal of Biological Chemistry. 265:21986-21991
Genomic and cDNA clones encoding the murine pulmonary surfactant protein SP-C were isolated and sequenced to provide the primary amino acid sequence of the murine SP-C polypeptide and the structural organization of the SP-C gene locus. Murine SP-C is
Autor:
Jeffrey A. Whitsett, T R Korfhagen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 14:118-120
Autor:
T R, Korfhagen, J A, Whitsett
Publikováno v:
Chest. 111
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(9)
To determine the role of surfactant protein A (SP-A) in host defense, the murine SP-A locus was targeted by homologous recombination to produce mice lacking SP-A. SP-A -/- and control mice were infected with group B streptococcus (GBS) by intratrache
Publikováno v:
The American journal of physiology. 272(3 Pt 1)
In the present study we asked if surfactant metabolism was altered in surfactant protein (SP) A-deficient mice in vivo. Although previous studies in vitro demonstrated that SP-A modulates surfactant secretion and reuptake by type II cells, mice made
Publikováno v:
Current opinion in pediatrics. 6(3)
Lung gene expression is regulated by a complex interaction of autocrine, paracrine, and endocrine factors. With cloning of lung-specific genes, the mechanisms of transcriptional control of lung gene expression are beginning to be deciphered. This rev
Publikováno v:
The Journal of biological chemistry. 265(35)
Genomic and cDNA clones encoding the murine pulmonary surfactant protein SP-C were isolated and sequenced to provide the primary amino acid sequence of the murine SP-C polypeptide and the structural organization of the SP-C gene locus. Murine SP-C is
Publikováno v:
Proceedings, annual meeting, Electron Microscopy Society of America. 54:14-15
A wide variety of growth factors are thought to be involved in the regulation of pre- and postnatal lung maturation, including factors which bind to the epidermal growth factor receptor. Marked pulmonary fibrosis and enlarged alveolar air spaces have
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 126:S75