Zobrazeno 1 - 10
of 70
pro vyhledávání: '"T R, Van De Water"'
Autor:
Jaime Marco, Ly Vu, JM Láinez, T. R. Van De Water, Chhavi Gupta, John Dinh, Esperanza Bas, F Martinez-Soriano
Publikováno v:
British Journal of Pharmacology. 166:1888-1904
BACKGROUND AND PURPOSE Exposure to an ototoxic level of an aminoglycoside can result in hearing loss. In this we study investigated the otoprotective efficacy of dexamethasone (DXM), melatonin (MLT) and tacrolimus (TCR) in gentamicin (GM)-treated ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b408f8c8fbf13e45e73d34f1fa43b71
https://doi.org/10.1111/j.1476-5381.2012.01890.x
https://doi.org/10.1111/j.1476-5381.2012.01890.x
Autor:
Christine T. Dinh, Scott M. Haake, T. R. Van De Water, Kimberly Hoang, Adrien A. Eshraghi, Shibing Chen, Th.J. Balkany, E. Nong
Publikováno v:
Neuroscience. 157:405-413
Objective: Determine the molecular mechanism(s) behind tumor necrosis factor-alpha (TNFα)–induced loss of auditory hair cells and the ability of dexamethasone base (DXMb) to protect against TNFα ototoxicity. Methods: Hair cell counts: Three-day-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3fe560b82a6bd7c5515a1b6fea2ae9
https://doi.org/10.1016/j.neuroscience.2008.09.012
https://doi.org/10.1016/j.neuroscience.2008.09.012
Autor:
François Lallemend, Brigitte Malgrange, T. R. Van De Water, Gustave Moonen, Grégory Hans, Jean-Michel Rigo, Philippe Lefèbvre
Publikováno v:
Journal of Neurochemistry. 87:508-521
In the current study, we have investigated the ability of substance P (SP) to protect 3-day-old (P3) rat spiral ganglion neurons (SGNs) from trophic factor deprivation (TFD)-induced cell death. The presence of SP high affinity neurokinin-1 receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cecf2355f00ea0bdf08cea6d7c2f291a
https://doi.org/10.1046/j.1471-4159.2003.02014.x
https://doi.org/10.1046/j.1471-4159.2003.02014.x
Autor:
Christine T. Dinh, Jorge Bohorquez, T. R. Van De Water, Ralph Abi-Hachem, Simon I. Angeli, Adrien A. Eshraghi
Publikováno v:
Scopus-Elsevier
Dexamethasone is a synthetic corticosteroid that is routinely administered via intratympanic injections for the treatment of sudden idiopathic sensorineural hearing loss (Plontke et al., 2009) with...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4308ef96b352097703c16a5f23426a
https://doi.org/10.1179/146701011x13001035753254
https://doi.org/10.1179/146701011x13001035753254
Autor:
Michel Eybalin, Ruth Lloyd, F. François, H. Jia, Jean-Luc Puel, Frédéric Venail, T. R. Van De Water, Jérôme Bourien
Publikováno v:
Neuroscience. 316
Cochlear fibrosis is a common finding following cochlear implantation. Evidence suggests that cochlear fibrosis could be triggered by inflammation and epithelial-to-mesenchymal cell transition (EMT). In this study, we investigate the mechanisms of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66a0dea901c0b917de1f5bc21eb13da
https://pubmed.ncbi.nlm.nih.gov/26718602
https://pubmed.ncbi.nlm.nih.gov/26718602
Supernumerary Outer Hair Cells Arise External to the Last Row of Sensory Cells in the Organ of Corti
Autor:
Gustave Moonen, Marc Thiry, T. R. Van De Water, Ingrid Breuskin, Brigitte Malgrange, Philippe Lefebvre
Publikováno v:
Acta Oto-Laryngologica. 121:164-168
During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa603e2f681508f8afae7c07e1fb2dd
https://doi.org/10.1080/000164801300043325
https://doi.org/10.1080/000164801300043325
Autor:
Hinrich Staecker, T. R. Van De Water, Brigitte Malgrange, Philippe Lefèbvre, Allen F. Ryan, Stefan Dazert
Publikováno v:
International Journal of Developmental Neuroscience. 15:553-562
To determine if transforming growth factor alpha (TGF alpha) pretreatment protects hair cells from aminoglycoside induced injury by modifying their intracellular calcium concentration, we assayed hair cell calcium levels in organ of Corti explants bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491de10c7f919ff2aa66808919e841e8
https://doi.org/10.1016/s0736-5748(96)00110-4
https://doi.org/10.1016/s0736-5748(96)00110-4
Autor:
Hinrich Staecker, T. R. Van De Water, Brigitte Malgrange, Gustave Moonen, Philippe Lefèbvre, Didier Martin
Publikováno v:
NeuroReport. 7:2495-2500
CONFOCAL analysis of early postnatal auditory neurones in a bicompartmental culture system was used to test for chemoattractant properties of NGF, BDNF and NT-3 on neuronal process outgrowth. NT-3 exerted a strong tropic effect on neuritic outgrowth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44c365663822c09bdd1a29fa81d96bc
https://doi.org/10.1097/00001756-199611040-00019
https://doi.org/10.1097/00001756-199611040-00019
Autor:
Gustave Moonen, Philippe Lefebvre, Wei Liu, Hinrich Staecker, Brigitte Malgrange, T. R. Van De Water, Christopher J. Hartnick
Publikováno v:
Journal of Neurobiology. 30:246-254
SUMMARY The neuronal survival promoting ability of brain derived neurotrophic factor (BDNF), and ciliary neurotrophic factor (CNTF), individually and in combination, was evaluated in dissociated cell cultures of postnatal day 5 (P5) rat acoustic gang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ed02d73ad5a18a1ca5fcb286a7b3ee
https://doi.org/10.1002/(sici)1097-4695(199606)30:2<246::aid-neu6>3.0.co
https://doi.org/10.1002/(sici)1097-4695(199606)30:2<246::aid-neu6>3.0.co
Autor:
Gustave Moonen, V. Galinovic-Schwartz, M. Moghadassi, Hinrich Staecker, Wei Liu, Philippe Lefebvre, Brigitte Malgrange, T. R. Van De Water
Publikováno v:
Developmental Brain Research. 92:49-60
Developing cochleovestibular ganglion (CVG) neurons depend upon interaction with the otocyst, their peripheral target tissue, for both trophic support and tropic guidance. RT-PCR of E11 through E14 otocyst-CVG RNA extracts have shown that NGF as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e9a5e09d390a56d768f6a18cb74558
https://doi.org/10.1016/0165-3806(95)00198-0
https://doi.org/10.1016/0165-3806(95)00198-0