Zobrazeno 1 - 3
of 3
pro vyhledávání: '"T R, Ryder"'
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57e2051d73da3ccf5d1890fbbd61bad3
https://doi.org/10.1002/chin.199737246
https://doi.org/10.1002/chin.199737246
Autor:
L Y, Hu, T R, Ryder, M F, Rafferty, K M, Siebers, T, Malone, A, Chatterjee, M R, Feng, S M, Lotarski, D M, Rock, S J, Stoehr, C P, Taylor, M L, Weber, G P, Miljanich, E, Millerman, B G, Szoke
Publikováno v:
Drug design and discovery. 17(1)
Several novel N-type voltage sensitive calcium channel blockers showed high affinity in the IMR32 assay and efficacy in the anti-writhing model. Herein, we describe the design, synthesis, SAR studies, biological data, physicochemical properties and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::382704345de2c1326eb0cae55033ad48
https://pubmed.ncbi.nlm.nih.gov/10928451
https://pubmed.ncbi.nlm.nih.gov/10928451
Autor:
T R, Ryder, L Y, Hu, M F, Rafferty, S M, Lotarski, D M, Rock, S J, Stoehr, C P, Taylor, M L, Weber, G P, Miljanich, E, Millerman, B G, Szoke
Publikováno v:
Drug design and discovery. 16(4)
Exploration of the SAR around the leucine side chain in a series of N,N-dialkyldipeptidylamines with potent functional activity at N-type VSCC is presented. A novel analog is disclosed which possesses improved aqueous solubility, in vivo activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::181b431799a8847399920bf609953e41
https://pubmed.ncbi.nlm.nih.gov/10807036
https://pubmed.ncbi.nlm.nih.gov/10807036