Zobrazeno 1 - 10
of 100
pro vyhledávání: '"T R, Ryder"'
Publikováno v:
ChemInform. 28
Autor:
L Y, Hu, T R, Ryder, M F, Rafferty, K M, Siebers, T, Malone, A, Chatterjee, M R, Feng, S M, Lotarski, D M, Rock, S J, Stoehr, C P, Taylor, M L, Weber, G P, Miljanich, E, Millerman, B G, Szoke
Publikováno v:
Drug design and discovery. 17(1)
Several novel N-type voltage sensitive calcium channel blockers showed high affinity in the IMR32 assay and efficacy in the anti-writhing model. Herein, we describe the design, synthesis, SAR studies, biological data, physicochemical properties and p
Autor:
T R, Ryder, L Y, Hu, M F, Rafferty, S M, Lotarski, D M, Rock, S J, Stoehr, C P, Taylor, M L, Weber, G P, Miljanich, E, Millerman, B G, Szoke
Publikováno v:
Drug design and discovery. 16(4)
Exploration of the SAR around the leucine side chain in a series of N,N-dialkyldipeptidylamines with potent functional activity at N-type VSCC is presented. A novel analog is disclosed which possesses improved aqueous solubility, in vivo activity in
Publikováno v:
Organic & Biomolecular Chemistry; 9/14/2024, Vol. 22 Issue 34, p6999-7005, 7p
Autor:
Wang, Shan1 (AUTHOR), Shi, Lou1 (AUTHOR), Chen, Xiao‐Yi1 (AUTHOR), Shu, Wei1,2 (AUTHOR) shuw@sustech.edu.cn
Publikováno v:
Angewandte Chemie. 5/22/2023, Vol. 135 Issue 22, p1-8. 8p.
Autor:
Grigolo, Thiago A.1 (AUTHOR), Smith, Joel M.1 (AUTHOR) smith@chem.fsu.edu
Publikováno v:
Chemistry - A European Journal. 12/9/2022, Vol. 28 Issue 69, p1-6. 6p.
Autor:
Georgieva, Miglena K.1 (AUTHOR) miggeo@fct.unl.pt, Santos, A. Gil1 (AUTHOR) agos@fct.unl.pt
Publikováno v:
European Journal of Organic Chemistry. 12/6/2022, Vol. 2022 Issue 45, p1-13. 13p.
Autor:
Muller, Jason, Marchisio, Luca, Attia, Rym, Zedet, Andy, Maradan, Robin, Vallet, Maxence, Aebischer, Alison, Harakat, Dominique, Senejoux, François, Ramseyer, Christophe, Foley, Sarah, Cardey, Bruno, Girard, Corine, Pudlo, Marc
Publikováno v:
RSC Medicinal Chemistry; May2024, Vol. 15 Issue 5, p1722-1730, 9p
Autor:
He, Yue‐Wei1 (AUTHOR), Wu, Wen‐Tao1 (AUTHOR), Han, Ying1 (AUTHOR) hanying@yzu.edu.cn, Ma, Wei‐Qing1 (AUTHOR), Sun, Jing1 (AUTHOR), Yan, Chao‐Guo1 (AUTHOR) cgyan@yzu.edu.cn
Publikováno v:
ChemistrySelect. 6/13/2022, Vol. 7 Issue 22, p1-5. 5p.
Autor:
Hillenbrand, Julius1 (AUTHOR), Korber, J. Nepomuk1 (AUTHOR), Leutzsch, Markus1 (AUTHOR), Nöthling, Nils1 (AUTHOR), Fürstner, Alois1 (AUTHOR) fuerstner@kofo.mpg.de
Publikováno v:
Chemistry - A European Journal. 10/7/2021, Vol. 27 Issue 56, p14025-14033. 9p.