Výsledky vyhledávání - "T R, Rosenstock"

Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice

Autor: T R, Rosenstock, C R A, Bertoncini, A V, Teles, H, Hirata, M J S, Fernandes, S S, Smaili

Publikováno v: The European journal of neuroscience. 32(1)

Huntington's disease is a neurodegenerative disorder caused by an expansion of CAGs repeats and characterized by alterations in mitochondrial functions. Although changes in Ca(2+) handling have been suggested, the mechanisms involved are not complete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53f969563aa033ac7c79102fd62f381b
https://pubmed.ncbi.nlm.nih.gov/20608968

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Mitochondrial calcium, oxidative stress and apoptosis in a neurodegenerative disease model induced by 3-nitropropionic acid

Autor: T R, Rosenstock, A C P, Carvalho, A, Jurkiewicz, R, Frussa-Filho, S S, Smaili

Publikováno v: Journal of neurochemistry. 88(5)

Intracellular calcium homeostasis is important for cell survival. However, increase in mitochondrial calcium (Ca2+m) induces opening of permeability transition pore (PTP), mitochondrial dysfunction and apoptosis. Since alterations of intracellular Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::845e8d15b55983a6b1126fafde007787
https://pubmed.ncbi.nlm.nih.gov/15009678

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