Výsledky vyhledávání

Folic acid pathway single nucleotide polymorphisms associated with methotrexate significant adverse events in United States veterans with rheumatoid arthritis

Autor: L A, Davis, B, Polk, A, Mann, R K, Wolff, G S, Kerr, A M, Reimold, G W, Cannon, T R, Mikuls, L, Caplan

Publikováno v: Clinical and experimental rheumatology. 32(3)

Methotrexate (MTX) is the cornerstone medication in the treatment of rheumatoid arthritis (RA). We examined whether single nucleotide polymorphisms (SNPs) in enzymes of the folic acid pathway (folylpoly-gamma-glutamate synthetase [FPGS], gamma-glutam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3dbd545afefd4d4ce685ccc7886b2ce5
https://pubmed.ncbi.nlm.nih.gov/24447348

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Poor to modest agreement between rheumatoid arthritis response measures in clinical practice

Autor: K, Michaud, T R, Mikuls, S E, Call, A M, Reimold, R, Hooker, G S, Kerr, J S, Richards, L, Caplan, G W, Cannon

Publikováno v: Clinical and experimental rheumatology. 27(4)

To evaluate the agreement among several rheumatoid arthritis (RA) response measures in a clinical setting.529 patients with RA were seen at 2 regular visits where the following response measures were determined: ACR-20, EULAR good or moderate (EULAR-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b0602ee7acc40cb6354a33b17ffd76c
https://pubmed.ncbi.nlm.nih.gov/19772796

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Quality of care in gout: from measurement to improvement

Autor: T R, Mikuls

Publikováno v: Clinical and experimental rheumatology. 25(6 Suppl 47)

Gout is a growing health problem, affecting approximately 7% of men and 3% of women over the age of 65 years. Although effective therapies for gout management exist, quality in gout care has been too frequently characterized as being "suboptimal." Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f15b83c00d1361941cf0f046509e73b
https://pubmed.ncbi.nlm.nih.gov/18021516

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Early rheumatoid arthritis in African-Americans: the CLEAR Registry

Autor: S L, Bridges, L B, Hughes, T R, Mikuls, G, Howard, H K, Tiwari, G S, Alarcón, J M, McNicholl, L W, Moreland

Publikováno v: Clinical and experimental rheumatology. 21(5 Suppl 31)

African-Americans have been under-represented in genetic studies of rheumatoid arthritis (RA) susceptibility and severity. Genetic and non-genetic factors influencing the radiographic severity of RA and its response to treatment are poorly understood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::270917440306dfe2c31d22d3be5cdc46
https://pubmed.ncbi.nlm.nih.gov/14969066

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