Zobrazeno 1 - 7
of 7
pro vyhledávání: '"T R, Barfknecht"'
Publikováno v:
Environmental and molecular mutagenesis. 36(1)
Octamethylcyclotetrasiloxane (OMCTS; CAS No. 556-67-2) was evaluated in a genetic toxicity battery. In preincubation tests with Salmonella typhimurium strains TA98, TA100, TA1535, TA1537, and TA1538, no mutagenicity was detected (maximum dose = 5 mg/
Publikováno v:
Cell Biology and Toxicology. 4:199-209
The results presented in this report demonstrate that an 18-20 hour exposure/3H-thymidine DNA labeling period is superior to a 4 hour incubation interval for general genotoxicity screening studies in the rat primary hepatocyte DNA repair assay. When
Autor:
M. Toraason, J. S. Bohrman, Richard W. Niemeier, D. K. Gulati, T. R. Barfknecht, B. L. Dames, R. Langenbach, JeAnne R. Burg, E. Elmore
Publikováno v:
Environmental and molecular mutagenesis. 12(1)
Three laboratories participated in an interlaboratory study to evaluate the usefulness of the Chinese hamster V79 cell metabolic cooperation assay to predict the tumor-promoting activity of selected chemicals. Twenty-three chemicals of different chem
Autor:
T R, Barfknecht, D M, Shankel
Publikováno v:
Mutation research. 30(2)
When the excision proficient strain E. coli WP2 Hcr+ trp- was grown to stationary phase by glucose starvation in M-9 minimal medium before UV -irradiation, the ability of nutrient broth enrichment of minimal medium to enhance trp- leads to Trp+ rever
Autor:
T R, Barfknecht, J B, Little
Publikováno v:
Cancer research. 42(4)
Fibroblast cell strains derived from different patients all afflicted with genetic predisposing to the development of intestinal polyposis and cancer were tested for their sensitivity to the lethal effects of the DNA alkylating agents methylmethanesu
Publikováno v:
Cell biology and toxicology. 3(2)
Several variations on the standard primary rat hepatocyte DNA/repair assay were evaluated for their ability to enhance the sensitivity of this genotoxicity test system. The use of hamster hepatocytes proved to be a much more sensitive system than rat
Publikováno v:
Developments in toxicology and environmental science. 10