Zobrazeno 1 - 10
of 134
pro vyhledávání: '"T Prendergast"'
Autor:
Kelly M. Potter, Jason N. Kennedy, Chukwudi Onyemekwu, Niall T. Prendergast, Pratik P. Pandharipande, E Wesley Ely, Christopher Seymour, Timothy D. Girard
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104942- (2024)
Summary: Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subt
Externí odkaz:
https://doaj.org/article/cc520dd1c1d545d68d1c1dc5a2e0c85e
Autor:
Catriona T. Prendergast, Robert A. Benson, Hannah E. Scales, Caio Santos Bonilha, John J. Cole, Iain McInnes, James M. Brewer, Paul Garside
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Mechanisms governing entry and exit of immune cells into and out of inflamed joints remain poorly understood. We sought herein to identify the key molecular pathways regulating such migration. Using murine models of inflammation in conjunction with m
Externí odkaz:
https://doaj.org/article/5d1175430835444c926fbbd904727585
Autor:
Daniel Paape, Catriona T. Prendergast, Helen P. Price, Johannes S. P. Doehl, Deborah F. Smith
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract Background Proving that specific genes are essential for the intracellular viability of Leishmania parasites within macrophages remains a challenge for the identification of suitable targets for drug development. This is especially evident i
Externí odkaz:
https://doaj.org/article/463f0595daaf427186f4594b3dbf6a5a
Autor:
Shaima Al Khabouri, Robert A. Benson, Catriona T. Prendergast, Joshua I. Gray, Thomas D. Otto, James M. Brewer, Paul Garside
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Effective tolerogenic intervention in Rheumatoid Arthritis (RA) will rely upon understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of endogenous CD4 T cell infiltrates in early inflammatory arthritis was asse
Externí odkaz:
https://doaj.org/article/f24f091353d845b49a310b48bae536ce
Autor:
Niall T. Prendergast, Chukwudi A. Onyemekwu, Kelly M. Potter, Perry J. Tiberio, Alison E. Turnbull, Timothy D. Girard
Publikováno v:
Journal of Intensive Care Medicine. 38:208-214
Importance: Agitation is common in mechanically ventilated ICU patients, but little is known about physician attitudes regarding agitation in this setting. Objectives: To characterize physician attitudes regarding agitation in mechanically ventilated
Akademický článek
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Publikováno v:
Clinics in chest medicine. 43(3)
Delirium, often underdiagnosed in the intensive care unit, is a common complication of critical illness that contributes to significant morbidity and mortality. Clinicians should be aware of common risk factors and triggers and should work to mitigat
Akademický článek
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Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004911 (2016)
In a murine model of repeated exposure of the skin to infective Schistosoma mansoni cercariae, events leading to the priming of CD4 cells in the skin draining lymph nodes were examined. The dermal exudate cell (DEC) population recovered from repeated
Externí odkaz:
https://doaj.org/article/3d59119ecf844210b0c3cd3de0d02111
Autor:
Helen P. Price, Catriona T. Prendergast, Daniel Paape, Deborah F. Smith, Johannes S. P. Doehl
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-16 (2020)
Parasites & Vectors
Parasites & Vectors
BackgroundProving that specific genes are essential for the intracellular viability ofLeishmaniaparasites within macrophages remains a challenge for the identification of suitable targets for drug development. This is especially evident in the absenc