Zobrazeno 1 - 10
of 50
pro vyhledávání: '"T Peeyush Kumar"'
Autor:
Kanako Matsumura, T. Peeyush Kumar, Tejesh Guddanti, Yuanqing Yan, Spiros L. Blackburn, Devin W. McBride
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 8 (2019)
Background Because of the failure of numerous clinical trials, various recommendations have been made to improve the usefulness of preclinical studies. Specifically, the STAIR (Stroke Therapy Academic Industry Roundtable) recommendations highlighted
Externí odkaz:
https://doaj.org/article/839af7ea25684063b473c1bb783ef1f5
Autor:
Jayanarayanan Sadanandan, Sithara Thomas, Iny Elizabeth Mathew, Zhen Huang, Spiros L Blackburn, Nitin Tandon, Hrishikesh Lokhande, Pierre D McCrea, Emery H. Bresnick, Pramod K Dash, Devin McBride, Arif Harmanci, Dania Jose, Ari C Dienel, Hussein A Zeineddine, Sungha Hong, T Peeyush Kumar
The blood-brain barrier (BBB) controls the movement of molecules into and out of the central nervous system (CNS). Since a functional BBB forms by mouse embryonic day E15.5, we reasoned that gene cohorts expressed in CNS endothelial cells (EC) at E13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ee6b9f1bc79dbc71afa03110ab0119
https://doi.org/10.1101/2022.11.29.516809
https://doi.org/10.1101/2022.11.29.516809
Autor:
Devin W. McBride, Huimahn A Choi, T Peeyush Kumar, Kanako Matsumura, Spiros Blackburn, Ari Dienel, Remya A Veettil
Publikováno v:
Stroke. 52
Subarachnoid hemorrhage induces neuronal apoptosis which causes acute and long-term memory deficits. Ourhypothesis is that agonism of α7-acetylcholine receptors attenuates neuronal apoptosis and improves memorydeficits in SAH mice. Mice were randoml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d14684f6304d00e7bbcda2c11081eb4
https://doi.org/10.1161/str.52.suppl_1.p783
https://doi.org/10.1161/str.52.suppl_1.p783
Autor:
T Peeyush Kumar, Kanako Matsumura, Louise D. McCullough, Sung Ha Hong, Ari Dienel, Leomar Y. Ballester, Devin W. McBride, Yuanqing Yan, Spiros Blackburn, Remya A Veettil, Sean P. Marrelli
Publikováno v:
Stroke
Background and Purpose: Delayed neurological deficits are a devastating consequence of subarachnoid hemorrhage (SAH), which affects about 30% of surviving patients. Although a very serious concern, delayed deficits are understudied in experimental SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756e14b239bf576e52c7b57a86992722
https://pubmed.ncbi.nlm.nih.gov/32539672
https://pubmed.ncbi.nlm.nih.gov/32539672
Autor:
Spiros Blackburn, Devin W. McBride, Ari Dienel, Remya A Veettil, Kanako Matsumura, T Peeyush Kumar
Publikováno v:
Stroke. 51
Rationale: Microthrombosis has been suggested as a major factor contributing to delayed neurological deterioration in patients after subarachnoid hemorrhage (SAH). However, experimental studies on the role of microthrombi in delayed deficits after SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb8559d9192d1c5993328936f6071ac
https://doi.org/10.1161/str.51.suppl_1.wp308
https://doi.org/10.1161/str.51.suppl_1.wp308
Autor:
Devin W. McBride, Spiros Blackburn, T Peeyush Kumar, Alba Rubi, Kanako Matsumura, Pramod K. Dash
Publikováno v:
Molecular Neurobiology. 56:1992-2006
In the brain, vascular endothelial cells conserve blood viscosity, control blood flow, and form the interface between central nervous system and circulating blood. Clinical outcome after aneurysmal subarachnoid hemorrhage is linked to early brain inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41539848af8a9f095eb54b2965e4de5
https://doi.org/10.1007/s12035-018-1213-7
https://doi.org/10.1007/s12035-018-1213-7
Autor:
Kanako Matsumura, Remya A Veettil, Jaroslaw Aronowski, Devin W. McBride, Pramod K. Dash, Ari Dienel, H. Alex Choi, T Peeyush Kumar, Andrey S. Tsvetkov, Spiros Blackburn
Publikováno v:
Exp Neurol
Subarachnoid hemorrhage (SAH) results in severe neuronal dysfunction and degeneration. Since the nicotinic acetylcholine α(7) receptors (α(7)-AChR) are involved in neuronal function and survival, we investigated if stimulation of α(7)-AChR would p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770a31948f6d41462d05510095f0a4af
https://doi.org/10.1016/j.expneurol.2021.113792
https://doi.org/10.1016/j.expneurol.2021.113792
Autor:
Spiros Blackburn, Tejesh Guddanti, Yuanqing Yan, Kanako Matsumura, Devin W. McBride, T Peeyush Kumar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Because of the failure of numerous clinical trials, various recommendations have been made to improve the usefulness of preclinical studies. Specifically, the STAIR (Stroke Therapy Academic Industry Roundtable) recommendations highlighted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5672a68428041feb0cc3218d457517e
https://pubmed.ncbi.nlm.nih.gov/30971151
https://pubmed.ncbi.nlm.nih.gov/30971151
Autor:
Stephen Capone, Spiros Blackburn, Kanako Matsumura, Devin W McBride, Tejesh Guddanti, T Peeyush Kumar
Publikováno v:
Stroke. 50
Rationale: Microthrombosis has been suggested as a major factor contributing to delayed neurological deterioration in patients after subarachnoid hemorrhage (SAH). Autopsy studies in humans show microthrombi throughout the brain in SAH patients. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fb925ef9b3a4be9ba00c88fbb4c10fa
https://doi.org/10.1161/str.50.suppl_1.tp328
https://doi.org/10.1161/str.50.suppl_1.tp328
Autor:
Zeineddine, Hussein A., Li, Wen, T, Peeyush Kumar, McBride, Devin, Dienel, Ari, Torres, Glenda, Grotta, James, Savarraj, Jude, Chang, Tiffany, Choi, Huimahn A., Dash, Pramod, Blackburn, Spiros
Publikováno v:
Stroke (00392499); Jun2022, Vol. 53 Issue 6, pe221-e223, 3p