Výsledky vyhledávání

Drug monitoring of antiretroviral therapy for HIV-1 infection: method validation and results of a pilot study

Autor: T P, Moyer, Z, Temesgen, R, Enger, L, Estes, J, Charlson, L, Oliver, A, Wright

Publikováno v: Clinical chemistry. 45(9)

Antiretroviral therapy for HIV-1 infection has become increasingly complex. The availability of new and potent drugs and progress in understanding the pathogenesis of HIV-1 infection have led to the establishment of new treatment paradigms. The varyi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed2f1880a0adca8fff9b63d94cd62442
https://pubmed.ncbi.nlm.nih.gov/10471649

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Supporting pharmaceutical studies for FDA submissions: diversifying the drug monitoring laboratory

Autor: T P, Moyer, L K, Oliver

Publikováno v: Clinical chemistry. 44(2)

Well-founded pharmacokinetic information is one of the cornerstones of a New Drug Application (NDA) to the Food and Drug Administration (FDA) required to introduce a new drug or a generic equivalent (ANDA) to the marketplace. The service that laborat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ebdf6f6cb4cafe03ce550e99b5e38911
https://pubmed.ncbi.nlm.nih.gov/9474056

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The importance of urinary magnesium values in patients with gut failure

Autor: Vilia Tarrosa, T P Moyer, C R Fleming, Gary Stoner, L George

Publikováno v: Mayo Clinic proceedings. 71(1)

To determine whether urinary magnesium (Mg) values in patients with gut failure would be more helpful than serum Mg measurements in assessment of Mg deficiency.We compared serum and urinary Mg values in 16 patients with gut failure and 16 age- and se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c086085be101e9207b3bc80867ae803
https://pubmed.ncbi.nlm.nih.gov/8538226

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Guamanian neurodegenerative disease: investigation of the calcium metabolism/heavy metal hypothesis

Autor: J E, Ahlskog, S C, Waring, L T, Kurland, R C, Petersen, T P, Moyer, W S, Harmsen, D M, Maraganore, P C, O'Brien, C, Esteban-Santillan, V, Bush

Publikováno v: Neurology. 45(7)

There is a high prevalence of neurodegenerative disease (parkinsonism, dementia, and motor neuron disease) on the western Pacific island of Guam. We sought evidence in support of the hypothesis that these conditions are triggered by nutritional defic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5989bf3192da59a50bbcd97162f7168b
https://pubmed.ncbi.nlm.nih.gov/7617195

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Effects of insulin on plasma magnesium in noninsulin-dependent diabetes mellitus: evidence for insulin resistance

Autor: Sean F. Dinneen, T. P. Moyer, A. Alzaid, Robert A. Rizza

Publikováno v: The Journal of clinical endocrinology and metabolism. 80(4)

Insulin influences both glucose metabolism and magnesium homeostasis in humans. The present studies sought to determine whether insulin-induced stimulation of magnesium uptake is impaired in noninsulin-dependent diabetes mellitus (NIDDM) and enhanced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0118a230de9fca955da7cec913cb272a
https://pubmed.ncbi.nlm.nih.gov/7714113

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Essential and toxic element concentrations in fresh and formalin-fixed human autopsy tissues

Autor: V J, Bush, T P, Moyer, K P, Batts, J E, Parisi

Publikováno v: Clinical chemistry. 41(2)

The concentrations of five essential elements and six potentially toxic elements were determined in seven organs collected at autopsy from 30 human subjects. Elemental analyses were carried out by graphite furnace atomic absorption spectroscopy, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3bae1636b8164212f0599f714c9fd81c
https://pubmed.ncbi.nlm.nih.gov/7874782

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Arsenic analysis II: rapid separation and quantification of inorganic arsenic plus metabolites and arsenobetaine from urine

Autor: D E, Nixon, T P, Moyer

Publikováno v: Clinical chemistry. 38(12)

We describe the rapid separation of inorganic arsenic plus metabolites from arsenobetaine or seafood arsenic in urine. Traditional, high-pressure liquid chromatography is replaced by disposable silica-based cation-exchange cartridges for this separat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a64dcd44292277c3d5b148d9e1ae4f19
https://pubmed.ncbi.nlm.nih.gov/1458588

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Total arsenic in urine: palladium-persulfate vs nickel as a matrix modifier for graphite furnace atomic absorption spectrophotometry

Autor: D E, Nixon, G V, Mussmann, S J, Eckdahl, T P, Moyer

Publikováno v: Clinical chemistry. 37(9)

We evaluated the effectiveness of nickel and palladium with or without added potassium persulfate as matrix modifiers for the determination of total arsenic in urine. Complete recovery of pure aqueous solutions of As(III), As(V), cacodylic acid (DMA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7139fbf32fdf8b6b45342293e50537b0
https://pubmed.ncbi.nlm.nih.gov/1893592

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