Zobrazeno 1 - 10
of 27
pro vyhledávání: '"T P Bender"'
Autor:
Urikhan Sanzhaeva, Helen Boyd-Pratt, Philip T. R. Bender, Thamaraiselvi Saravanan, Scott B. Rhodes, Tongju Guan, Neil Billington, Shannon E. Boye, Christopher L. Cunningham, Charles T. Anderson, Visvanathan Ramamurthy
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Microtubules are essential for various cellular processes. The functional diversity of microtubules is attributed to the incorporation of various α- and β-tubulin isotypes encoded by different genes. In this work, we investigated the funct
Externí odkaz:
https://doaj.org/article/2bce1a002054404696b0451fc39c920b
Autor:
D. Emmert, N. Szczypien, Tim T. A. Bender, L. Grigull, A. Gass, C. Link, F. Klawonn, R. Conrad, M. Mücke, J. Sellin
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background and objective The diagnosis of rare diseases (RDs) is often challenging due to their rarity, variability and the high number of individual RDs, resulting in a delay in diagnosis with adverse effects for patients and healthcare sys
Externí odkaz:
https://doaj.org/article/a5bb9d09d8b2460aa5a151bacade242a
Therapeutic options for patients with rare rheumatic diseases: a systematic review and meta-analysis
Autor:
Tim T. A. Bender, Judith Leyens, Julia Sellin, Dmitrij Kravchenko, Rupert Conrad, Martin Mücke, Matthias F. Seidel
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-16 (2020)
Abstract Background Rare diseases (RDs) in rheumatology as a group have a high prevalence, but randomized controlled trials are hampered by their heterogeneity and low individual prevalence. To survey the current evidence of pharmacotherapies for rar
Externí odkaz:
https://doaj.org/article/fd1944b1aa634326bdb770bf2e153bf1
Autor:
Yu. N. Bykov, T. B. Bender, Yu. N. Vasiliev, A. N. Kalyagin, Т. М. Maksikova, G. M. Orlova, N. M. Kozlova, O. V. Ryzhkova
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 10, Iss 4, Pp 65-71 (2018)
Motor and non-motor symptoms are identified in the clinical picture of Parkinson's disease (PD). Among its non-motor manifestations, cognitive impairment (CI) and emotional disorders play a special role in PD. It is important to search for new forms
Externí odkaz:
https://doaj.org/article/f7da02c79b8744dc89bba433d3d93b4b
Autor:
Y. N. Bykov, T. B. Bender
Publikováno v:
Acta Biomedica Scientifica, Vol 3, Iss 1, Pp 60-65 (2018)
Parkinson's disease is a long-term degenerative disorder of the central nervous system. Parkinson's disease typically occurs in people over the age of 60, of which about one percent are affected. Clinical features of Parkinson's disease consist of mo
Externí odkaz:
https://doaj.org/article/71c85654274a449f83334a54d89e5172
Autor:
Y. N. Bykov, T. B. Bender
Publikováno v:
Acta Biomedica Scientifica, Vol 1, Iss 3(1), Pp 65-71 (2016)
The review concerns modern pharmacological methods of Parkinson's disease treatment. The basic drugs used in practice are levodopa, dopamine receptor agonists, MAO-B inhibitors, anticholinergics, COMT inhibitors, and amantadine drugs. The article con
Externí odkaz:
https://doaj.org/article/d7637ef0dae24212bac37b15159635d2
Autor:
C, Müller, R, Yang, G, Idos, N, Tidow, S, Diederichs, O M, Koch, W, Verbeek, T P, Bender, H P, Koeffler
Publikováno v:
Blood. 94:4255-4262
Cyclin A1 differs from other cyclins in its highly restricted expression pattern. Besides its expression during spermatogenesis, cyclin A1 is also expressed in hematopoietic progenitor cells and in acute myeloid leukemia. We investigated mechanisms t
Publikováno v:
The Journal of Immunology. 148:934-942
The expression of c-myb mRNA is differentially regulated in murine B lymphoid tumors such that B cell lymphomas and plasmacytomas contain significantly less c-myb mRNA than pre-B cell lymphomas. To examine the low level of c-myb mRNA expression in th
Autor:
M H, Jeng, M A, Shupnik, T P, Bender, E H, Westin, D, Bandyopadhyay, R, Kumar, S, Masamura, R J, Santen
Publikováno v:
Endocrinology. 139(10)
Hormone-dependent breast cancer responds to primary therapies that block estrogen production or action, but tumor regrowth often occurs 12-18 months later. Additional hormonal treatments that further reduce estrogen synthesis or more effectively bloc
Publikováno v:
Oncogene. 9(7)
Src family protein tyrosine kinases (PTKs) actively participate in signal transduction during lymphocyte activation. However, little is known about the roles of PTKs and their substrates in lymphocyte differentiation. To identify PTK substrates that