Zobrazeno 1 - 10
of 49
pro vyhledávání: '"T P, Storozhevykh"'
Autor:
T. P. Storozhevykh, L. A. Andreeva, Pinelis Vg, Ya. E. Senilova, N. F. Myasoyedov, G. R. Tukhbatova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:601-604
Semax (100 microM) and its Pro-Gly-Pro fragment (20 and 100 microM) delayed the development of calcium dysregulation and reduction of the mitochondrial potential in cultured cerebellar granule cells under conditions of glutamate neurotoxicity. Incuba
Autor:
Pinelis Vg, V. P. Reutov, T. P. Storozhevykh, Oleg Granstrem, E. G. Sorokina, Ya. E. Senilova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 142:51-54
Rabbit antibodies against GluR1 subunit of AMPA glutamate receptors in a concentration of 1 mug/ml significantly increased intracellular Ca(2+)concentration and decreased mitochondrial potential in hippocampal neurons, i.e. produced changes typical o
Publikováno v:
Bulletin of Experimental Biology and Medicine. 137:453-456
The effect of thrombin, an agonist of proteinase-activated receptor (PAR) family, was studied on cultured rat hippocampal neurons. Thrombin in a concentration range of 1 pM - 10 nM induced a transitory dose-dependent increase in intracellular free ca
Publikováno v:
Bulletin of Experimental Biology and Medicine. 135:139-142
Combined blockade of Na+/Ca2+ exchange, Ca2+ uptake by mitochondria and endoplasmic reticulum usually does not prevent recovery of the basal level of intracellular Ca2+ after 1-min action of glutamate (100 μM) or K+ (50 mM). However, replacement of
Publikováno v:
Bulletin of Experimental Biology and Medicine. 131:440-443
Using primary cultures of cerebellar granule cells we showed that Ca2+ transported into neurons under the effect of glutamate is accumulated and stored in mitochondria for a long time. Protonophore FCCP, an uncoupler of oxidative phosphorylation, sti
Autor:
E. G. Sorokina, N. Grigortsevich, T. P. Storozhevykh, Pinelis Vg, N. Vinskaya, B. I. Khodorov
Publikováno v:
FEBS Letters. 448:173-176
In experiments with fura-2 loaded cultured rat cerebellar granule cells we have compared the changes in [Ca2+]i homeostasis produced by replacement of external Na+ with the organic cation N-methyl-d-glucamine (NMDG) or Li+. The Na+/NMDG replacement c
Autor:
O. Vergun, Pinelis Vg, N. Vinskaya, N. Grigortsevich, B. I. Khodorov, E. G. Sorokina, T. P. Storozhevykh
Publikováno v:
FEBS Letters. 431:215-218
In cultured rat cerebellar granule cells an inhibition of plasma membrane Na+/Ca2+ exchange by removal of external Na+ (replacement with NMDG) caused an increase in [Ca2+]i at rest and a considerable delay in [Ca2+]i recovery from Glu-imposed [Ca2+]i
Publikováno v:
FEBS Letters. 397:230-234
The purpose of our work was to study the relationship between glutamate (GLU)-induced mitochondrial depolarization and deterioration of neuronal Ca2+ homeostasis following a prolonged GLU challenge. The experiments were performed on cultured rat cere
Autor:
V. B. Koshelev, E. N. Arsen'eva, O. E. Fadyukov, V. G. Pinelis, T. P. Storozhevykh, T. V. Ryasina, F. Z. Meerson, E. Ya. Vorontsova, T. B. Mareeva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 117:125-128
Exposure of Krushinsky-Molodkina rats (a strain genetically predisposed to audiogenic epilepsy) to multiple electrostimulation (a course consisting of 10 sessions) prolongs the latency of epileptic seizures, lowers blood levels of stress hormones, le
Autor:
Pierre Braquet, T. P. Storozhevykh, M. A. Medvedev, Kh. M. Markov, D. V. Zagulova, M. R. Baskakov, Pinelis Vg, E. Chabrier
Publikováno v:
Bulletin of Experimental Biology and Medicine. 116:1227-1230
Endothelin (ET) is a peptide produced by the cells of the vascular endothel ium and is one of the most effective endogenous vasoconstrictive agents. The first reports on its isolation, purification, and synthesis appeared in 1987-88 [2]. In the inter