Zobrazeno 1 - 10
of 59
pro vyhledávání: '"T P, Quinn"'
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Pathways into care-homes have been under-researched. Individuals who move-in to a care-home from hospital are clinically distinct from those moving-in from the community. However, it remains unclear whether the source of care-home
Externí odkaz:
https://doaj.org/article/db0f574abd24458d957925af2407443e
Autor:
Matthew R. Stoyek, Sarah E. Doane, Shannon E. Dallaire, Zachary D. Long, Jessica M. Ramia, Donovan L. Cassidy-Nolan, Kar-Lai Poon, Thomas Brand, T. Alexander Quinn
Publikováno v:
Genes, Vol 15, Iss 3, p 280 (2024)
Popeye domain-containing (POPDC) proteins selectively bind cAMP and mediate cellular responses to sympathetic nervous system (SNS) stimulation. The first discovered human genetic variant (POPDC1S201F) is associated with atrioventricular (AV) block, w
Externí odkaz:
https://doaj.org/article/804431a0feb8444f8ae740ced1cc5ad2
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
In the adult heart, acute adaptation of electrical and mechanical activity to changes in mechanical load occurs via feedback processes known as “mechano-electric coupling” and “mechano-mechanical coupling.” Whether this occurs during cardiac
Externí odkaz:
https://doaj.org/article/ac96dca868404c76992da6675c28be03
Autor:
P. M. Kiffney, P. J. Lisi, M. Liermann, S. M. Naman, J. H. Anderson, M. H. Bond, G. R. Pess, M. E. Koehler, E. R. Buhle, T. W. Buehrens, R. S. Klett, J. M. Cram, T. P. Quinn
Publikováno v:
Ecosphere, Vol 14, Iss 2, Pp n/a-n/a (2023)
Abstract Mobile species are particularly affected by artificial barriers requiring large investments to restore connectivity. However, few large‐scale, long‐term studies have investigated the ecological outcomes of restoring connectivity for thes
Externí odkaz:
https://doaj.org/article/aa8a9c8dbe6145b4af281648dd1732df
Publikováno v:
Systematic Reviews, Vol 10, Iss 1, Pp 1-11 (2021)
Abstract Background There is growing interest in the use of routine patient-reported outcome measures (PROMs) to influence the care of individual patients with stroke. However, there are significant gaps in our understanding as to how PROMs influence
Externí odkaz:
https://doaj.org/article/59772a9423d9444c841c4a9eebfb6e91
Autor:
A. Vilches-Moraga, A. Price, P. Braude, L. Pearce, R. Short, A. Verduri, M. Stechman, J. T. Collins, E. Mitchell, A. G. Einarsson, S. J. Moug, T. J. Quinn, B. Stubbs, K. McCarthy, P. K. Myint, J. Hewitt, B. Carter, on behalf of the COPE Study
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background The COVID-19 pandemic has placed significant pressure on health and social care. Survivors of COVID-19 may be left with substantial functional deficits requiring ongoing care. We aimed to determine whether pre-admission frailty wa
Externí odkaz:
https://doaj.org/article/babcf0afd45f40a98f0d84a8839beaab
Autor:
Matthew R. Stoyek, Eilidh A. MacDonald, Melissa Mantifel, Jonathan S. Baillie, Bailey M. Selig, Roger P. Croll, Frank M. Smith, T. Alexander Quinn
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cardiac excitation originates in the sinoatrial node (SAN), due to the automaticity of this distinct region of the heart. SAN automaticity is the result of a gradual depolarisation of the membrane potential in diastole, driven by a coupled system of
Externí odkaz:
https://doaj.org/article/e9ef0578676e48a39c4578966db61b36
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Optogenetics, involving the optical measurement and manipulation of cellular activity with genetically encoded light-sensitive proteins (“reporters” and “actuators”), is a powerful experimental technique for probing (patho-)physiological func
Externí odkaz:
https://doaj.org/article/bfca15ba8c2c4411a1345b196c636867
Autor:
Eilidh A. MacDonald, Josef Madl, Joachim Greiner, Ahmed F. Ramadan, Sarah M. Wells, Angelo G. Torrente, Peter Kohl, Eva A. Rog-Zielinska, T. Alexander Quinn
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The rhythmic electrical activity of the heart’s natural pacemaker, the sinoatrial node (SAN), determines cardiac beating rate (BR). SAN electrical activity is tightly controlled by multiple factors, including tissue stretch, which may contribute to
Externí odkaz:
https://doaj.org/article/a223c688e90a4c52a6f06f0565159a4c
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Introduction: In ventricular myocytes, spontaneous release of calcium (Ca2+) from the sarcoplasmic reticulum via ryanodine receptors (“Ca2+ sparks”) is acutely increased by stretch, due to a stretch-induced increase of reactive oxygen species (RO
Externí odkaz:
https://doaj.org/article/fc1c2a7d08cd4719a1e0cea463ff6f5f