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Autor:
S, Hoffenberg, T M, Shannon, T P, Noonan, S, Liu, D S, Daniel, J B, Fishman, J B, Rubins, H K, Misra, G E, Wright, B F, Dickey
Publikováno v:
Molecular pharmacology. 49(1)
G proteins are molecular switches that use a cycle of GTP binding and hydrolysis to regulate a wide variety of cellular biochemical processes. Because the functional state of these proteins is allosterically determined by bound guanine nucleotides, a