Zobrazeno 1 - 10
of 34
pro vyhledávání: '"T P, Kennedy"'
Autor:
Upkar S Gill, Patrick T F Kennedy, Andrew Hall, Rageshri Dhairyawan, Alberto Quaglia, James M Harris, Colin Nixon, Fadi Issa, Amy Cross, Edward Arbe-Barnes, Jane A McKeating, Dimitra Peppa
Publikováno v:
eGastroenterology, Vol 2, Iss 3 (2024)
Background and aims The intrahepatic processes associated with chronic hepatitis B (CHB), especially in the context of hepatitis delta virus (HDV) and HIV co-infection, require a better understanding. Spatial transcriptomics can provide new insights
Externí odkaz:
https://doaj.org/article/fc1ee0e355574540accc5e4589a7d9e0
Autor:
A. G. Jones, S. A. Marcott, A. L. Gorin, T. M. Kennedy, J. D. Shakun, B. M. Goehring, B. Menounos, D. H. Clark, M. Romero, M. W. Caffee
Publikováno v:
The Cryosphere, Vol 17, Pp 5459-5475 (2023)
There is unambiguous evidence that glaciers have retreated from their 19th century positions, but it is less clear how far glaciers have retreated relative to their long-term Holocene fluctuations. Glaciers in western North America are thought to hav
Externí odkaz:
https://doaj.org/article/041669e0ced74dd08408f1b09db498c1
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
Background and aimsChronic hepatitis B (CHB) and non-alcoholic fatty liver disease (NAFLD) are leading causes of liver-related morbidity and mortality. The interaction between these two disease processes is poorly defined and the impact of NAFLD on H
Externí odkaz:
https://doaj.org/article/8dab092abcaa43bba659aeea37cb9876
Autor:
Romina Salpini, Stefano D’Anna, Livia Benedetti, Lorenzo Piermatteo, Upkar Gill, Valentina Svicher, Patrick T. F. Kennedy
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Chronic infection with Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and mortality worldwide. HBV-DNA integration into the human genome is recognized as a frequent event occurring during the early phases of HBV infection and cha
Externí odkaz:
https://doaj.org/article/92bb7c3f0a074acfb9c5fa08946552cc
Autor:
Young-Suk Lim, W. Ray Kim, Douglas Dieterich, Jia-Horng Kao, John F. Flaherty, Leland J. Yee, Lewis R. Roberts, Homie Razavi, Patrick T. F. Kennedy
Publikováno v:
Viruses, Vol 15, Iss 4, p 997 (2023)
Chronic hepatitis B (CHB) is the most common cause of hepatocellular carcinoma (HCC) worldwide. Antiviral treatment reduces the risk of HCC and mortality; nonetheless, globally in 2019, only 2.2% of CHB patients received treatment. Current internatio
Externí odkaz:
https://doaj.org/article/b0f820d04b534e6eae9f1231aec2919b
Autor:
Carla Usai, Joseph M. Gibbons, Corinna Pade, Wenhao Li, Sabina R. M. Jacobs, Áine McKnight, Patrick T. F. Kennedy, Upkar S. Gill
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundThe presentation of SARS-CoV-2 infection varies from asymptomatic to severe COVID-19. Similarly, high variability in the presence, titre and duration of specific antibodies has been reported. While some host factors determining these differ
Externí odkaz:
https://doaj.org/article/ba889035419841beb5f4fb551228df61
Publikováno v:
Viruses, Vol 14, Iss 5, p 900 (2022)
Chronic hepatitis B (CHB) is associated with significant morbidity and mortality, due to the adverse sequelae of cirrhosis and hepatocellular carcinoma (HCC). To date, antiviral therapy has been reserved for patients with ostensibly active liver dise
Externí odkaz:
https://doaj.org/article/c501602f7d17494c8e76d0a526786b72
Autor:
Lorenzo Piermatteo, Mohammad Alkhatib, Stefano D’Anna, Vincenzo Malagnino, Ada Bertoli, Eleonora Andreassi, Elisa Basile, Alessandra Iuvara, Maria De Cristofaro, Giuseppina Cappiello, Carlotta Cerva, Carmine Minichini, Mariantonietta Pisaturo, Mario Starace, Nicola Coppola, Carla Fontana, Sandro Grelli, Francesca Ceccherini-Silberstein, Massimo Andreoni, Upkar S. Gill, Patrick T. F. Kennedy, Loredana Sarmati, Romina Salpini, Valentina Svicher
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1352 (2021)
HBeAg is a marker of HBV-activity, and HBeAg-loss predicts a favorable clinical outcome. Here, we characterize HBeAg-levels across different phases of HBV infection, their correlation with virological/biochemical markers and the virological response
Externí odkaz:
https://doaj.org/article/fc62f2e8dcdf48d9a45d80e5744a1f28
Autor:
Harsimran D. Singh, Itziar Otano, Krista Rombouts, Kasha P. Singh, Dimitra Peppa, Upkar S. Gill, Katrin Böttcher, Patrick T. F. Kennedy, Jude Oben, Massimo Pinzani, Henning Walczak, Giuseppe Fusai, William M. C. Rosenberg, Mala K. Maini
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The TRAIL pathway can mediate apoptosis of hepatic stellate cells to promote the resolution of liver fibrosis. However, TRAIL has the capacity to bind to regulatory receptors in addition to death-inducing receptors; their differential roles
Externí odkaz:
https://doaj.org/article/0c84e0f5a1504bfe85b9a7ea0c3a5f5a
Autor:
Iain T R Kennedy, Albert J van Hoek, Sonia Ribeiro, Hannah Christensen, W John Edmunds, Mary E Ramsay, Shamez N Ladhani
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177082 (2017)
The short-term impact of childhood invasive meningococcal disease (IMD) on quality-of-life (QoL) remains largely unquantified. This study aimed to quantify QoL loss at the point when illness was at its worst, and assess health state recovery in the m
Externí odkaz:
https://doaj.org/article/3262958d5b0147e1be54891ea4e36ef8