Zobrazeno 1 - 9 of 9 pro vyhledávání: '"T P, Jerussi"'
1
Differential effects of spinal (R)-ketoprofen and (S)-ketoprofen against signs of neuropathic pain and tonic nociception: evidence for a novel mechanism of action of (R)-ketoprofen against tactile allodynia
Autor: Frank Porreca, H. Sun, K. Ren, T. P. Jerussi, Michael H. Ossipov
Publikováno v: Pain. 87:193-199
The spinal activity of racemic ketoprofen and its enantiomers in models of neuropathic and tonic pain was explored in rats. Tactile allodynia and thermal hyperalgesia were induced by tight ligation of the L(5)/L(6) spinal nerves. Tonic pain was model
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565a7fd50f02f70b2e8a6457652b6f94
https://doi.org/10.1016/s0304-3959(00)00280-3
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3
New 1-(heterocyclylalkyl)-4-(propionanilido)-4-piperidinyl methyl ester and methylene methyl ether analgesics
Autor: J. R. Bagley, Theodore C. Spaulding, B. M. Doorley, S A Thomas, Michael H. Ossipov, Frieda G. Rudo, H. K. Spencer, Mark J. Benvenga, T. P. Jerussi
Publikováno v: Journal of Medicinal Chemistry. 34:827-841
A series of new 1-(heterocyclyalkyl)-4-(propionanilido)-4-piperidinyl methyl esters and methylene methyl ethers have been synthesized and pharmacologically evaluated. In the mouse hot-plate test, the majority of compounds exhibited an analgesia (ED50
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b2488784bafa855e397dd63e2b3563
https://doi.org/10.1021/jm00106a051
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4
Pre- and post-synaptic actions of apomorphine: differentiation by rotatory effects in normal rats
Autor: S D, Glick, T P, Jerussi, R D, Cox, L N, Fleisher
Publikováno v: Archives internationales de pharmacodynamie et de therapie. 225(2)
Normal rats were tested for rotation (circling behavior) following d-amphetamine (1.0 mg/kg) and, a week later, following apomorphine (10.0 mg/kg). In most rats, d-amphetamine and apomorphine elicited rotation in opposite directions whereas, in some
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4385acef5221c6595406c0d7912fecd5
https://pubmed.ncbi.nlm.nih.gov/557962
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7
Cholinergic features of photoreceptor synapses in Hermissenda
Autor: D. L. Alkon, Yoram Grossman, T. P. Jerussi, E. Heldman
Publikováno v: Journal of neurophysiology. 42(1 Pt 1)
1. A number of observations, as listed below, suggested a cholinergic basis for inhibitory interactions between photoreceptors of the eye in the nudibranch mollusk Hermissenda crassicornis. 2. The isolated eyes synthesized and accumulated acetylcholi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737ac5be8d10a39898303708750aa1ac
https://pubmed.ncbi.nlm.nih.gov/34673
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9
Circling behavior in mice and rats: possible relationship to isolation-induced aggression
Autor: T. P. Jerussi, J. F. Hyde
Publikováno v: Experientia. 41(3)
The relationship between circling behavior (rotation), isolation, and aggression was investigated in normal male mice and rats. Initially the animals were tested for spontaneous nocturnal rotation, then conspecific aggression and muricidal behavior w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1231ff5ec9bdc5988d3b49bcd15a351f
https://pubmed.ncbi.nlm.nih.gov/4038662
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