Zobrazeno 1 - 10 of 43 pro vyhledávání: '"T P, Ciaraldi"'
1
Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes
Autor: Svetlana E. Nikoulina, Leslie Carter, Robert R. Henry, Sunder Mudaliar, Pharis Mohideen, T P Ciaraldi
Publikováno v: Diabetes. 49:263-271
Glycogen synthase (GS) activity is reduced in skeletal muscle of type 2 diabetes, despite normal protein expression, consistent with altered GS regulation. Glycogen synthase kinase-3 (GSK-3) is involved in regulation (phosphorylation and deactivation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12541e593fc4ea9639e0ee6685f7ca43
https://doi.org/10.2337/diabetes.49.2.263
Zobrazit plný text záznamu
3
Regulation of Glycogen Synthase Activity in Cultured Skeletal Muscle Cells From Subjects With Type II Diabetes: Role of Chronic Hyperinsulinemia and Hyperglycemia
Autor: R. R. Henry, Svetlana E. Nikoulina, Sunder Mudaliar, Kyong Soo Park, L. Abrams-Carter, T P Ciaraldi
Publikováno v: Diabetes. 46:1017-1024
Human skeletal muscle cultures (HSMCs) from type II diabetic subjects were used to determine whether metabolic abnormalities such as hyperglycemia or hyperinsulinemia contribute to the defective muscle glycogen synthase (GS) activity present in this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bf5e713b6c8c52212afc089b71be20
https://doi.org/10.2337/diab.46.6.1017
Zobrazit plný text záznamu
8
Rat fibroblast cells overexpressing kinase-inactive human insulin receptors are insulin responsive: influence of growth conditions
Autor: T P Ciaraldi, H E Khoo, K L Lim, Ellen H.-A. Wong, F H Ng, C.H. Tan
Publikováno v: Endocrinology. 136:1459-1467
The effects of insulin to stimulate metabolic and mitogenic responses were examined in Rat 1 fibroblast cells that overexpressed either normal (HIRc) or kinase-deficient human insulin receptors. When studied at the optimal growth stage for each cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885672fe3cb2af86c3bd1cc49daaf6c6
https://doi.org/10.1210/endo.136.4.7534700
Zobrazit plný text záznamu
9
Insulin-responsive human adipocytes express two glucose transporter isoforms and target them to different vesicles
Autor: W Wilkinson, T P Ciaraldi, T P Hueckstaedt, W T Garvey, Paul F. Pilch, Jerrold M. Olefsky
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 77:286-289
We have characterized the insulin-dependent increase in glucose transport in human adipocytes using subcellular fractionation and antibodies specific for the two isoforms of the glucose transporter that are expressed in these cells. Plasma membranes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668550e058ace21f6e29c5c1c2b85b27
https://doi.org/10.1210/jcem.77.1.8325954
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje