Výsledky vyhledávání - "T P, Bonnert"

theta, a novel gamma-aminobutyric acid type A receptor subunit

Autor: T P, Bonnert, R M, McKernan, S, Farrar, B, le Bourdellès, R P, Heavens, D W, Smith, L, Hewson, M R, Rigby, D J, Sirinathsinghji, N, Brown, K A, Wafford, P J, Whiting

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 96(17)

gamma-Aminobutyric acid type A (GABA-A) receptors are a major mediator of inhibitory neurotransmission in the mammalian central nervous system, and the site of action of a number of clinically important drugs. These receptors exist as a family of sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3c3ef7da5e042f2f2fb407d340913f3
https://pubmed.ncbi.nlm.nih.gov/10449790

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Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published]

Autor: P J, Whiting, G, McAllister, D, Vassilatis, T P, Bonnert, R P, Heavens, D W, Smith, L, Hewson, R, O'Donnell, M R, Rigby, D J, Sirinathsinghji, G, Marshall, S A, Thompson, K A, Wafford, D, Vasilatis

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 17(13)

We report the isolation and characterization of a cDNA encoding a novel member of the GABA receptor gene family, epsilon. This polypeptide is 506 amino acids in length and exhibits its greatest amino acid sequence identity with the GABAA receptor gam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24d1d5dbe38f8762a9e0757598a47772
https://pubmed.ncbi.nlm.nih.gov/9185540

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The cloning and characterization of human MyD88: a member of an IL-1 receptor related family

Autor: T P, Bonnert, K E, Garka, P, Parnet, G, Sonoda, J R, Testa, J E, Sims

Publikováno v: FEBS letters. 402(1)

Murine MyD88, an RNA with homology both to the interleukin-1 receptor signaling domain and to 'death-domains', is rapidly upregulated during differentiation of the myeloleukemic cell line M1. We have cloned the human homologue of murine MyD88 and re-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6db9223aa404c0aa0ef20675c0b1e7a9
https://pubmed.ncbi.nlm.nih.gov/9013863

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By-passing immunization. Human antibodies from V-gene libraries displayed on phage

Autor: J D, Marks, H R, Hoogenboom, T P, Bonnert, J, McCafferty, A D, Griffiths, G, Winter

Publikováno v: Journal of molecular biology. 222(3)

We have mimicked features of immune selection to make human antibodies in bacteria. Diverse libraries of immunoglobulin heavy (VH) and light (V kappa and V lambda) chain variable (V) genes were prepared from peripheral blood lymphocytes (PBLs) of uni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f30bc48531bdf3e083c464529c8f0df
https://pubmed.ncbi.nlm.nih.gov/1748994

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