Zobrazeno 1 - 10
of 12
pro vyhledávání: '"T P, Abrahams"'
Publikováno v:
Neurogastroenterology and Motility. 14:295-304
An understanding of the neural control of lower oesophageal sphincter (LOS) relaxation is clin- ically relevant because transient LOS relaxations (TLOSRs) are a mechanism of acid reflux into the oesophagus. Preganglionic motor neurones innervating th
Autor:
P J, Hornby, T P, Abrahams
Publikováno v:
Clinical Obstetrics and Gynecology. 39:17-35
This article reviews the basic principles of pharmacodynamics and pharmacokinetics, with a special emphasis on the pharmacologic considerations that must be taken into account when treating the patient with respiratory disease who is also pregnant or
Publikováno v:
Physiology & Behavior. 59:109-115
Recent evidence suggests that cocaine decreases rather than increases sympathetic nerve discharge (SND). The purpose of the present study was to provide the first complete characterization of the dose-response relationships of cocaine (0.005-3 mg/kg,
Autor:
Roisin T. Scullion, Joseph M. Moerschbaecher, E. R. Partosoedarso, T. P. Abrahams, Pamela J. Hornby
Publikováno v:
The Journal of physiology. 550(Pt 1)
Delta9-tetrahydrocannabinol (delta9-THC) is an effective anti-emetic; however, other potential gastrointestinal therapeutic effects of delta9-THC are less well-known. Here, we report a role of delta9-THC in a vago-vagal reflex that can result in gast
Publikováno v:
The Journal of comparative neurology. 430(2)
The motor control of the lower esophageal sphincter (LES) is critical for normal swallowing and emesis, as well as for the prevention of gastroesophageal reflux. However, there are surprisingly few data on the central organization and neurochemistry
Publikováno v:
Journal of the autonomic nervous system. 77(2-3)
Vagal stimulation results in both gastric motor excitatory and non-adrenergic non-cholinergic (NANC) inhibitory responses. The NANC pathway involves preganglionic cholinergic neurons, which act through nicotinic receptors to ultimately evoke gastric
Publikováno v:
The American journal of physiology. 272(6 Pt 1)
Thyrotropin-releasing hormone (TRH) from the nucleus raphe obscurus (nROb) innervates the dorsal vagal complex (DVC) and activates gastric motor function. Assessment of the importance of TRH has been hampered by the lack of TRH receptor antagonists.
Publikováno v:
Journal of the autonomic nervous system. 58(3)
Recent studies have shown that cocaine decreases, rather than increases sympathetic nerve discharge (SND). Whether these sympathoinhibitory responses are the result of cocaine's actions on monoaminergic transmission (i.e. blockade of neuronal uptake
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 270(1)
Recent studies have reported that microinjection of kynurenic acid (KYN 12.5 nmol), the nonselective Excitatory Amino acid (EAA) antagonist, into the rostral ventrolateral medulla of the cat decreases arterial blood pressure (BP) and inferior cardiac
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(3)
The purpose of the present study was to identify sites(s) in the ventrolateral medulla where excitatory amino acids are involved in respiratory control. For this purpose, the respiratory effects produced by bilateral microinjection of excitatory amin