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pro vyhledávání: '"T Norman"'
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Informativeness, in the context of clinical trials, defines whether a study’s results definitively answer its research questions with meaningful next steps. Many clinical trials end uninformatively. Clinical trial protocols are
Externí odkaz:
https://doaj.org/article/760b2146c26e4de99e87463bef64ffe2
Autor:
Timo N. Haschler, Harry Horsley, Monika Balys, Glenn Anderson, Jan-Willem Taanman, Robert J. Unwin, Jill T. Norman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Ischemia is a major cause of kidney damage. Proximal tubular epithelial cells (PTECs) are highly susceptible to ischemic insults that frequently cause acute kidney injury (AKI), a potentially life-threatening condition with high mortality. A
Externí odkaz:
https://doaj.org/article/bf7c614184604ba8a7792b2421c0cbc7
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100013- (2021)
ADPKD is the most common genetic disease of the kidney leading to end-stage renal disease necessitating renal replacement therapy at any time between the 1st and 8th decades of life due to widely variable rates of disease progression. This presents s
Externí odkaz:
https://doaj.org/article/9b0f2d7fd2a145ee9ef3bcd43f6700ae
Autor:
Robert I. Menzies, John W.R. Booth, John J. Mullins, Matthew A. Bailey, Frederick W.K. Tam, Jill T. Norman, Robert J. Unwin
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 73-83 (2017)
Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be promoted by infiltration of circulating macrophages. Monocyte chemoattractant protein-1 (MCP-1)
Externí odkaz:
https://doaj.org/article/09543f448dd741b5bce76b3c6f64b596
Akademický článek
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Autor:
Meloni, Bruno P., Milani, Diego, Edwards, Adam B., Anderton, Ryan S., O'Hare Doig, Ryan L., Fitzgerald, Melinda, Palmer, T. Norman, Knuckey, Neville W.
Publikováno v:
In Pharmacology and Therapeutics September 2015 153:36-54
Autor:
Maxwell A. Astle, Andreas Weilhard, Graham A. Rance, Tara M. LeMercier, Craig T. Stoppiello, Luke T. Norman, Jesum Alves Fernandes, Andrei N. Khlobystov
Publikováno v:
ACS Applied Nano Materials. 5:2075-2086
Publikováno v:
Kidney360
Stages of CKD are currently defined by eGFR and require measurement of serum creatinine concentrations. Previous studies have shown a good correlation between salivary and serum urea levels and the stage of CKD. However, quantitative salivary urea as