Zobrazeno 1 - 10
of 30
pro vyhledávání: '"T N, Subbotina"'
Autor:
T. N. Subbotina, A. A. Shalyova, A. I. Shevchenko, E. A. Pozdysheva, Ya. A. Voytsekhovskaya, K. O. Mironov
Publikováno v:
Онкогематология, Vol 19, Iss 1, Pp 92-98 (2024)
Background. According to WHO guidelines, one of the criteria for diagnosis of polycythemia vera is the presence of somatic mutations in exon 12 of the JAK2 gene, but to date there is no universally accepted simple method to analyze these mutations. W
Externí odkaz:
https://doaj.org/article/3fc284f3fa844d70873a22080ed63bb9
Autor:
T. N. Subbotina, I. E. Maslyukova, K. S. Semashchenko, G. A. Khodos, D. V. Kurochkin, A. A. Shalyova, M. A. Mikhalev, E. V. Vasiliev, M. G. Osadchaya, E. A. Dunaeva, A. S. Esman, K. O. Mironov
Publikováno v:
Онкогематология, Vol 18, Iss 1, Pp 63-75 (2023)
Background. The development of myelofibrosis (MF) is driven by complex molecular genetic events that include driver somatic mutations responsible for the constitutive activation of the JAK/STAT signaling pathway (JAK2, CALR, and MPL), additional muta
Externí odkaz:
https://doaj.org/article/271d47d097ae4504ac8bd87fab744cd1
Publikováno v:
Онкогематология, Vol 17, Iss 4, Pp 118-125 (2022)
Background. The presence of the FLT3-ITD mutations in patients with AML serves as a marker of poor prognosis, which is included in the ELN 2017 risk stratification guideline. The main criterion for dividing patients into groups according to the predi
Externí odkaz:
https://doaj.org/article/949671ee51664c06bc72c94200295a60
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 18, Iss 3, Pp 289-296 (2022)
Aim. To study the association of nucleotide polymorphisms in platelet receptor and cytochrome P450 genes with the development of resistance to antiplatelet drugs in CHD patients.Material and Methods. The study included 243 patients diagnosed with CHD
Externí odkaz:
https://doaj.org/article/fd842221fda9496592f4ed26bc272272
Autor:
T. N. Subbotina, I. E. Maslyukova, D. V. Kurochkin, M. A. Mikhalev, M. G. Osadchaya, V. A. Khorzhevskiy, T. A. Garkusha, E. A. Dunaeva, K. O. Mironov
Publikováno v:
Онкогематология, Vol 17, Iss 2, Pp 30-35 (2022)
JAK2 mutations can be associated with any phenotypic form of chronic myeloproliferative neoplasia, while MPL and CALR mutations occur, as a rule, in cases of essential thrombocythemia and primary myelofibrosis and they are not observed in polycythemi
Externí odkaz:
https://doaj.org/article/47182056f2d748148f454fefc5457c9c
Autor:
T. N. Subbotina, D. V. Kurochkin, I. E. Maslyukova, A. S. Khazieva, E. V. Vasiliev, M. A. Mikhalev, E. A. Dunaeva, K. O. Mironov
Publikováno v:
Онкогематология, Vol 16, Iss 2, Pp 48-55 (2021)
Background. In accordance with the World health organization clinical guidelines, the analysis of somatic mutations in the CALR gene, as well as mutations in the JAK2 and MPL genes, are included in the list of criteria for the Ph-myeloproliferative n
Externí odkaz:
https://doaj.org/article/43c934e311f744ed94dab242733f6db9
Autor:
T. N. Subbotina, I. E. Maslyukova, A. A. Faleeva, P. A. Nikolaeva, A. S. Khazieva, E. A. Dunaeva, K. O. Mironov, L. B. Polushkina, I. S. Martynkevich, S. V. Vereshchagina, B. V. Barankin
Publikováno v:
Онкогематология, Vol 15, Iss 2, Pp 85-91 (2020)
Background. There are problems related to both quantitative assessment of an allele burden level of a mutant gene and interpretation of results in DNA samples with the burden level of the mutant allele less than 15–20 %, when using Sanger sequencin
Externí odkaz:
https://doaj.org/article/bc3b0376a2864fffaa914ecdf25e92fa
Autor:
A. A. Kosinova, T. S. Mongush, M. D. Goncharov, T. N. Subbotina, K. S. Semashchenko, G. Yu. Kochmareva, Yu. I. Grinshtein
Publikováno v:
Российский кардиологический журнал, Vol 0, Iss 10, Pp 22-28 (2019)
Aim. To study the association of T715P (rs6136), M62I (rs2228315), S290N (rs6131), V640L (rs6133) polymorphisms in the P-selectin gene with resistance to acetylsalicylic acid (ASA) in patients with coronary artery disease after coronary artery bypass
Externí odkaz:
https://doaj.org/article/c1b371fcc9074e5ca217137df155c3fc
Autor:
A. A. Kosinova, T. S. Mongush, M. D. Goncharov, T. N. Subbotina, K. S. Semashchenko, G. Y. Kochmareva, Yu. I. Grinshtein
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 15, Iss 3, Pp 343-348 (2019)
Aim. To study the association of V640L (rs6133) polymorphism in the P-selectin gene with acetylsalicylic acid (ASA) resistance in patients with coronary heart disease after coronary bypass surgery (CABG).Material and methods. The study included 104 p
Externí odkaz:
https://doaj.org/article/e2e9cf50c2244949b674b0c20b26f88f
Autor:
A. A. Razumova, T. N. Subbotina, D. V. Pokhabov, G. Y. Kochmaryova, A. A. Karnyushka, V. G. Abramov, S. V. Vereschagina
Publikováno v:
Russian neurological journal. 26:15-22
Background. Parkinson’s disease (PD) is one of the common neurodegenerative diseases. Several genes are known (SNCA, PARK2, PINK1, PARK7 (DJ-1) and LRRK2), mutations in which have a pathological significance in the development of monogenic PD; asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240a14df3d065462020e7cab51327d48
https://doi.org/10.30629/2658-7947-2021-26-4-15-22
https://doi.org/10.30629/2658-7947-2021-26-4-15-22