Výsledky vyhledávání - "T N, Mayadas"

Dimerization of P-selectin in platelets and endothelial cells

Autor: F J, Barkalow, K L, Barkalow, T N, Mayadas

Publikováno v: Blood. 96(9)

P-selectin is a leukocyte adhesion receptor stored in platelets and endothelial cells and is translocated to the surface upon cell activation. Purified P-selectin is oligomeric and has increased avidity for its ligand relative to the monomeric form,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::34df2e6fa31103b3085246e5142493fc
https://pubmed.ncbi.nlm.nih.gov/11049986

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Regulatory interactions of alphabeta and gammadelta T cells in glomerulonephritis

Autor: A R, Rosenkranz, S, Knight, S, Sethi, S I, Alexander, R S, Cotran, T N, Mayadas

Publikováno v: Kidney international. 58(3)

Several lines of evidence suggest that cellular immune mechanisms contribute to glomerulonephritis.The roles of alphabeta and gammadelta T cells in the pathogenesis of glomerulonephritis were investigated in a model of nephrotoxic nephritis in mice d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a1ceb991939f5d1390fa89bb2aaa97e
https://pubmed.ncbi.nlm.nih.gov/10972670

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Beta-glucan, a 'specific' biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18)

Autor: J, Yan, V, Vetvicka, Y, Xia, A, Coxon, M C, Carroll, T N, Mayadas, G D, Ross

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(6)

beta-Glucans were identified 36 years ago as a biologic response modifier that stimulated tumor rejection. In vitro studies have shown that beta-glucans bind to a lectin domain within complement receptor type 3 (CR3; known also as Mac-1, CD11b/CD18,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::878e9323ae3ff952fb8bccde547ed934
https://pubmed.ncbi.nlm.nih.gov/10477568

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Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression

Autor: N, Bhat, P Y, Perera, J M, Carboni, J, Blanco, D T, Golenbock, T N, Mayadas, S N, Vogel

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(12)

Taxol, a potent antitumor agent that binds beta-tubulin and promotes microtubule assembly, results in mitotic arrest at the G2/M phase of the cell cycle. More recently, Taxol was shown to be a potent LPS mimetic in murine, but not in human macrophage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f264dafeb38fec26568874e85ef8e849
https://pubmed.ncbi.nlm.nih.gov/10358184

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Impaired mast cell development and innate immunity in Mac-1 (CD11b/CD18, CR3)-deficient mice

Autor: A R, Rosenkranz, A, Coxon, M, Maurer, M F, Gurish, K F, Austen, D S, Friend, S J, Galli, T N, Mayadas

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(12)

Mac-1 (CD11b/CD18, CR3), a beta2 integrin expressed on leukocytes, is important in leukocyte migration. We demonstrate that Mac-1 is also expressed on peritoneal mast cells and LPS stimulated bone marrow-derived cultured mast cells, and that Mac-1-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::600cbf777ee001462ac8b4aa80753ce2
https://pubmed.ncbi.nlm.nih.gov/9862668

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Role of endothelial selectins in wound repair

Autor: M, Subramaniam, S, Saffaripour, L, Van De Water, P S, Frenette, T N, Mayadas, R O, Hynes, D D, Wagner

Publikováno v: The American journal of pathology. 150(5)

P- and E-selectins are adhesion molecules expressed on activated endothelium and platelets at sites of vascular injury and inflammation. The selectins are important for leukocyte recruitment. Because little is known about the role of selectins in wou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75362673a6fce1bd3126e53df51615f6
https://pubmed.ncbi.nlm.nih.gov/9137094

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Brain endothelium lack one of two pathways of P-selectin-mediated neutrophil adhesion

Autor: F J, Barkalow, M J, Goodman, M E, Gerritsen, T N, Mayadas

Publikováno v: Blood. 88(12)

P-selectin, an endothelial leukocyte adhesion receptor, is rapidly translocated to the cell surface upon release from storage granules called Weibel-Palade bodies and is also transcriptionally upregulated upon cytokine stimulation of endothelial cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6356e61669a49b30028b1f38599b142a
https://pubmed.ncbi.nlm.nih.gov/8977250

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Cultured murine cerebral microvascular endothelial cells contain von Willebrand factor-positive Weibel-Palade bodies and support rapid cytokine-induced neutrophil adhesion

Autor: F J, Barkalow, M J, Goodman, T N, Mayadas

Publikováno v: Microcirculation (New York, N.Y. : 1994). 3(1)

To obtain cultures of rodent brain microvascular endothelium (BMEC) that retain endothelial cell-specific markers and functions for two purposes: investigating whether these cultures contain endothelial cell-specific storage granules or Weibel-Palade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0d529a2768566d817de784ad016bf38
https://pubmed.ncbi.nlm.nih.gov/8846268

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Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin

Autor: S, Yamada, T N, Mayadas, F, Yuan, D D, Wagner, R O, Hynes, R J, Melder, R K, Jain

Publikováno v: Blood. 86(9)

P-selectin-mediated rolling is believed to be important in the recruitment of leukocytes to tissue after ischemia-reperfusion injury. The dorsal skin chamber was used to examine differences in the rolling and stable adhesion of circulating leukocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fb589d864216847d4a6c3a91e57b878d
https://pubmed.ncbi.nlm.nih.gov/7579454

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