Zobrazeno 1 - 10
of 10
pro vyhledávání: '"T N, Johansen"'
Autor:
Lotte Brehm, Hans Bräuner-Osborne, Frank A. Sløk, T. N. Johansen, Bjarke Ebert, Trine Meldgaard Lund, Povl Krogsgaard-Larsen, Ulf Madsen
Publikováno v:
European Journal of Medicinal Chemistry. 31:515-537
Publikováno v:
Bioorganic & Medicinal Chemistry. 3:553-558
The (R)- and (S)-forms of 2-amino-3-(3-hydroxyisoxazol-5-yl)propionic acid (homoibotenic acid, HIBO) were synthesized, using (S)-BOC-phenylalanine as a chiral auxiliary and their absolute stereochemistry correlated with that of (R)-Br-HIBO. The enant
Autor:
Ulf Madsen, Hans Braeuner‐Osborne, Povl Krogsgaard-Larsen, Frank A. Sloek, Trine Meldgaard Lund, T. N. Johansen, Lotte Brehm, Bjarke Ebert
Publikováno v:
ChemInform. 27
Autor:
Diane Zimmermann, Bjarke Ebert, Povl Krogsgaard-Larsen, Lotte Brehm, Ulf Madsen, Hans Braeuner‐Osborne, Yves L. Janin, T. N. Johansen
Publikováno v:
ChemInform. 31
Autor:
T N, Johansen, T B, Stensbøl, B, Nielsen, S B, Vogensen, K, Frydenvang, F A, Sløk, H, Bräüner-Osborne, U, Madsen, P, Krogsgaard-Larsen
Publikováno v:
Chirality. 13(9)
We have previously described (RS)-2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) as a potent agonist at the (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor subtype of (S)-glutamic acid (Glu) receptors.
Autor:
S B, Vogensen, H S, Jensen, T B, Stensbøl, K, Frydenvang, B, Bang-Andersen, T N, Johansen, J, Egebjerg, P, Krogsgaard-Larsen
Publikováno v:
Chirality. 12(10)
We have previously shown that (RS)-2-amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)isoxazol -4-yl] propionic acid (2-Me-Tet-AMPA) is a selective agonist at (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptors, markedly mo
Autor:
E H, Møller, J, Egebjerg, L, Brehm, T B, Stensbøl, T N, Johansen, U, Madsen, P, Krogsgaard-Larsen
Publikováno v:
Chirality. 11(10)
The phosphono amino acid, (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl+ ++]propio nic acid (ATPO), is a structural hybrid between the NMDA antagonist (RS)-2-amino-7-phosphonoheptanoic acid (AP7) and the AMPA and GluR5 agonist, (RS)-
Publikováno v:
Biochemistry. 35(20)
The structure of the (-)-(7S,8R,9S,10R)-N6-[10-(7,8,910-tetrahydrobenzo [a]pyrenyl)]-2'-deoxyadenosyl adduct at X6 of 5'-d(CGGACXAGAAG)-3'-5'-d(CTTCTTGTCCG)-3', derived from trans addition of the exocyclic N6-amino group of dA to (-)-(7S,8R,9R,10S)-7
Publikováno v:
Advances in experimental medicine and biology. 287
Autor:
Bjarke Ebert, Bruce E. Jones, Povl Krogsgaard-Larsen, Ulf Madsen, John Wm. Ferkany, Tina Holm, T. N. Johansen
Publikováno v:
European journal of pharmacology. 189(6)
The two heterocyclic aspartic acid and glutamic acid analogues derived from ibotenic acid, (RS)-2-amino-2-(3-hydroxy-5-methylisoxazol-4-yl)acetic acid (AMAA) and (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) have previously be