Zobrazeno 1 - 10
of 11
pro vyhledávání: '"T N, Bogatyrenko"'
Autor:
T. N. Bogatyrenko, N. V. Kandalintseva, T. E. Sashenkova, U. Yu. Allayarova, D. V. Mishchenko
Publikováno v:
Russian Chemical Bulletin. 71:517-523
Publikováno v:
Russian Chemical Bulletin. 69:1999-2003
The effect of 2-ethyl-3-hydroxy-6-methylpyridine nitroxy succinate (1) on heart, brain, and liver tissues of experimental animals (C57/b1 mice) was studied by EPR. It was shown that compound 1, like nicorandil, increases the nitric oxide production i
Publikováno v:
Russian Chemical Bulletin. 68:174-180
The effect of citrulline and ammonium chloride on the nitric oxide formation by peritoneal macrophages and liver tissue cells was studied using ESR spectroscopy. In ex vivo models, the incubation of cells capable of expressing inducible NO synthase (
Publikováno v:
Russian Chemical Bulletin. 67:700-704
Due to the multifactorial nature of cancer diseases, investigations of combinations of the known cytostatics with substances that are chemosensitizers and act on various molecular target in the organism gain increasing significance. Polyfunctional co
Autor:
T. E. Sashenkova, Nina P. Konovalova, V. R. Bogatyrenko, T. N. Bogatyrenko, Z. V. Kuropteva, D. V. Mishchenko, L. M. Bayder
Publikováno v:
Russian Chemical Bulletin. 65:561-565
The present investigation is based on the paradoxical dichotomy of the biological action of nitric oxide (NO). Depending on its concentration in the organism, it can have therapeutic or pathogenic effect. It was shown that during the treatment with c
Antioxidant Properties of a Pharmaceutical Substance Hypocard, a Potential Drug for Ischemic Disease
Autor:
Elena F. Shevtsova, Sergey G. Klochkov, T. N. Bogatyrenko, D. V. Mishchenko, Margarita E. Neganova
Publikováno v:
Bulletin of experimental biology and medicine. 166(1)
Antioxidant activity of a pharmaceutical substance hypocard was compared with activity of nitromalic acid and well-known agents nicorandil and Mexidol. The ability of these substances to inhibit spontaneous and oxidant-induced LPO process in rat brai
Polyfunctional action of biologically active compounds in antitumor chemotherapy of cyclophosphamide
Autor:
T. E. Sashenkova, Z. V. Kuropteva, A. M. Sipyagin, Nina P. Konovalova, V. R. Bogatyrenko, T. N. Bogatyrenko, L. M. Baider, Fedorov Boris S
Publikováno v:
Russian Chemical Bulletin. 63:1187-1191
Combinations of the known cytostatic cyclophosphamide (cyclophosphan) with hydroxamic acids (asparagylhydroxamic and salicylhydroxamic), nitric oxide donor (sodium nitrate), and an original hybrid non-steroidal anti-inflammatory compound, viz., diclo
Autor:
L. M. Baider, Fedorov Boris S, T. N. Bogatyrenko, V. R. Bogatyrenko, Nina P. Konovalova, Z. V. Kuropteva
Publikováno v:
Russian Chemical Bulletin. 60:1162-1165
Taking into account the data on oxidative transformation of hydroxamic acids to form nitric oxide and the similarity of their structure to the hydroxyarginine group being involved in the NO synthesis, we performed the study of biotransformation of sa
[The use of hydroxamic acids and sodium nitrate to enhance the antitumor effect of cyclophosphamide]
Publikováno v:
Voprosy onkologii. 59(1)
It has been showed that the introduction of nitrocompounds (as nitic oxide donors) in to the compositions of cyclophosphamide and hydroxamic acids for curing animals having leukemia P-388 increased duration of life by 290%. Thereby 40% of animals hav
Autor:
N D, Goncharova, V Iu, Marenin, T E, Oganian, A V, Shmaliĭ, T N, Bogatyrenko, L S, Kozina, V M, Prokopenko
Publikováno v:
Advances in gerontology = Uspekhi gerontologii. 21(4)
The purpose of the investigation was to study age-related changes in reaction of the hypothalamic-pituitary-adrenal axis and erythrocyte antioxidant enzyme system in response to acute psychoemotional stress in non human primates. Ten young (6-8 years