Zobrazeno 1 - 10
of 523
pro vyhledávání: '"T Mcintosh"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
It remains unclear how spontaneous Pancreatic Ductal Adenocarcinoma (PDAC) tumors escape Yap dependency. Here, the authors show that lineage plasticity promotes spontaneous relapse following YAP ablation and reveal key transcriptional drivers that ov
Externí odkaz:
https://doaj.org/article/df63191ad5df4c8da8cf9519ea7988c1
Autor:
Changkun Hu, Taylor Bugbee, Rachel Palinski, Ibukun A Akinyemi, Michael T McIntosh, Thomas MacCarthy, Sumita Bhaduri-McIntosh, Nicholas Wallace
Publikováno v:
eLife, Vol 12 (2023)
Double strand breaks (DSBs) are one of the most lethal DNA lesions in cells. The E6 protein of beta-human papillomavirus (HPV8 E6) impairs two critical DSB repair pathways: homologous recombination (HR) and non-homologous end joining (NHEJ). However,
Externí odkaz:
https://doaj.org/article/b54c18b5addc4591aac934765ee5ce95
Autor:
Lihua Wang, Rachel Madera, Yuzhen Li, Douglas P. Gladue, Manuel V. Borca, Michael T. McIntosh, Jishu Shi
Publikováno v:
Viruses, Vol 15, Iss 4, p 863 (2023)
Neutralizing antibodies (nAbs) can be used before or after infection to prevent or treat viral diseases. However, there are few efficacious nAbs against classical swine fever virus (CSFV) that have been produced, especially the porcine-originated nAb
Externí odkaz:
https://doaj.org/article/5de860d963b241e49b470de77fc12fd6
Autor:
Tiffany R. Frey, Ibukun A. Akinyemi, Eric M. Burton, Sumita Bhaduri-McIntosh, Michael T. McIntosh
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) persist as life-long infections alternating between latency and lytic replication. Human endogenous retroviruses (HERVs), via integration into the
Externí odkaz:
https://doaj.org/article/c0dad7a305a64a3690f4aab081dbdaae
Autor:
Eric M Burton, Ibukun A Akinyemi, Tiffany R Frey, Huanzhou Xu, Xiaofan Li, Lai Jing Su, Jizu Zhi, Michael T McIntosh, Sumita Bhaduri-McIntosh
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009447 (2021)
Krüppel-associated box-domain zinc finger protein (KRAB-ZFP) transcriptional repressors recruit TRIM28/KAP1 to heterochromatinize the mammalian genome while also guarding the host by silencing invading foreign genomes. However, how a KRAB-ZFP recogn
Externí odkaz:
https://doaj.org/article/f207aa25a96d48058ad9fcf8b9c9ff9a
Autor:
Sascha James-Conterelli, Daihnia Dunkley, Jennifer T. McIntosh, Tamika Julien, Maurice D. Nelson, Angela Richard-Eaglin
Publikováno v:
The Nurse Practitioner. 48:23-32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ca1a49a9c026338eff1e017f755a6d
https://doi.org/10.1097/01.npr.0000000000000001
https://doi.org/10.1097/01.npr.0000000000000001
Autor:
Alec T McIntosh, Renhuizi Wei, Jaeil Ahn, Brad E Aouizerat, Seble G Kassaye, Michael H Augenbraun, Jennifer C Price, Audrey L French, Stephen J Gange, Kathryn M Anastos, Radoslav Goldman
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247277 (2021)
HIV coinfection is associated with more rapid liver fibrosis progression in hepatitis C (HCV) infection. Recently, much work has been done to improve outcomes of liver disease and to identify targets for pharmacological intervention in coinfected pat
Externí odkaz:
https://doaj.org/article/76f5d8eaaeba46409350200295f520aa
Autor:
Michael T McIntosh, Siva Koganti, J Lucas Boatwright, Xiaofan Li, Salvatore V Spadaro, Alexis C Brantly, Jasmine B Ayers, Ramon D Perez, Eric M Burton, Sandeepta Burgula, Thomas MacCarthy, Sumita Bhaduri-McIntosh
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008849 (2020)
Epstein-Barr virus (EBV) causes lymphomas and epithelial cell cancers. Though generally silent in B lymphocytes, this widely prevalent virus can cause endemic Burkitt lymphoma and post-transplant lymphoproliferative disorders/lymphomas in immunocompr
Externí odkaz:
https://doaj.org/article/d2e67ce9f71447bc9ee6a70bf7cf905c
Publikováno v:
International Journal of Clinical Pharmacy. 45:342-354
Background Several guidelines support polypharmacy management in individual patients. More organisational-level focus is needed on the use of implementation frameworks. Aim To characterise the peer reviewed literature on implementation frameworks, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44b19de47d9dbebcf4ecc260c27f8a3e
https://doi.org/10.1007/s11096-023-01534-8
https://doi.org/10.1007/s11096-023-01534-8
Publikováno v:
International Journal of Pharmacy Practice. 31:i15-i17
Introduction Limited evidence exists for independent prescribing in community pharmacy (CP) (1). In 2020 NHS Scotland launched NHS Pharmacy First Plus (PFP), aiming to facilitate access to pharmacist independent prescribers (PIPs) in CP, focusing on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a3f0cc9f29262e8dc3c43af71bbde41
https://doi.org/10.1093/ijpp/riad021.018
https://doi.org/10.1093/ijpp/riad021.018