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Akademický článek

Formaldehyde Exposure and Irritative Effects on Medical Examiners, Pathologic Anatomy Post-Graduate Students and Technicians

Autor: L Vimercati, A Carrus, T Martino, I Galise, V Minunni, F Caputo, A Dell'Erba, G Assennato

Publikováno v: Iranian Journal of Public Health, Vol 39, Iss 4, Pp 26-34 (2010)

"nBackground: Exposure to formaldehyde (FA) causes irritative effects and induces nasopharyngeal cancer; the International Agency for Research on Cancer (IARC, Lyon) classified FA as carcinogenic to humans, Group 1. Many studies have been published

Externí odkaz: https://doaj.org/article/e5a349c9296f402798886675149af932

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Akademický článek

Immune Response Mechanisms against AAV Vectors in Animal Models

Autor: Ashley T. Martino, David M. Markusic

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 198-208 (2020)

Early preclinical studies in rodents and other species did not reveal that vector or transgene immunity would present a significant hurdle for sustained gene expression. While there was early evidence of mild immune responses to adeno-associated viru

Externí odkaz: https://doaj.org/article/d05848937dce484ea4c82d56b45af200

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Akademický článek

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation

Autor: Ravikumar A. Sitapara, Alex G. Gauthier, Sergio I. Valdés-Ferrer, Mosi Lin, Vivek Patel, Mao Wang, Ashley T. Martino, Jeanette C. Perron, Charles R. Ashby, Kevin J. Tracey, Valentin A. Pavlov, Lin L. Mantell

Publikováno v: Molecular Medicine, Vol 26, Iss 1, Pp 1-12 (2020)

Abstract Background Oxygen therapy, using supraphysiological concentrations of oxygen (hyperoxia), is routinely administered to patients who require respiratory support including mechanical ventilation (MV). However, prolonged exposure to hyperoxia r

Externí odkaz: https://doaj.org/article/b13b623bd7544973bd280f95bda287a6

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Akademický článek

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