Zobrazeno 1 - 10
of 566
pro vyhledávání: '"T Makinodan"'
Publikováno v:
Radiation research. 139(1)
The proliferative response to mitogenic stimulation by splenocytes can be augmented by exposing mice to whole-body, chronic, intermittent low doses of ionizing radiation, referred to here as low-dose irradiation. The purpose of this study was to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::388ead3e9a9951c2dd419db91d3d92a9
https://pubmed.ncbi.nlm.nih.gov/8016307
https://pubmed.ncbi.nlm.nih.gov/8016307
Publikováno v:
Clinical immunology and immunopathology. 55(3)
Very low doses of ionizing radiation can enhance immune responsiveness and extend life span in normal mice. Total lymphoid irradiation at relatively high doses of radiation can retard autoimmune disease in genetically susceptible mice, but may impair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01c354e35e8e76f5193ccc668bd517ba
https://pubmed.ncbi.nlm.nih.gov/2340650
https://pubmed.ncbi.nlm.nih.gov/2340650
Publikováno v:
The Journal of Immunology. 129:2426-2430
Spleen and lymph node cells from young (3 to 4 months) and old (24 to 36 months) mice of two inbred lines and one hybrid stock were assessed for the effect of age on IL 2 production. The results revealed that the production of IL 2 by old spleen and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fcc4e0114b26e248ccbcae0eec71459
https://doi.org/10.4049/jimmunol.129.6.2426
https://doi.org/10.4049/jimmunol.129.6.2426
Autor:
T. Makinodan
Publikováno v:
Journal of the American Geriatrics Society. 24:249-252
Normal immune functions can begin to decline shortly after an individual reaches sexual maturity. Although changes in cellular environment are partially responsible, the decline is due primarily to changes within the cells, especially the T cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17530eb4ed0a171496054aa3c02f608e
https://doi.org/10.1111/j.1532-5415.1976.tb03299.x
https://doi.org/10.1111/j.1532-5415.1976.tb03299.x
Decline in the growth potential of spleen-colonizing bone marrow stem cells of long-lived aging mice
Autor:
T. Makinodan, Julia W. Albright
Publikováno v:
The Journal of Experimental Medicine
The growth capacity of femoral bone marrow stem cells from young and old long-lived mice was assessed in the spleen of X-irradiated young and old syngeneic recpients by determining: (a) the number of stem cells colonizing the spleen, (b) the rate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7166b52c1e299b7d1bb74ad9d827d38b
http://europepmc.org/articles/PMC2190459
http://europepmc.org/articles/PMC2190459
Autor:
Katsuiku Hirokawa, T. Makinodan
Publikováno v:
The Journal of Immunology. 114:1659-1664
The thymus of long-lived BC3F1 mice involutes progressively throughout life, beginning at 6 weeks of age. This is manifested by the loss of cortical lymphoid mass and by the degenerative changes in epithelial cells. The purpose of this study was to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c8beb5686d2d526917fc70d0d72113
https://doi.org/10.4049/jimmunol.114.6.1659
https://doi.org/10.4049/jimmunol.114.6.1659
Publikováno v:
Clinical Immunology and Immunopathology. 5:371-376
At attempt has been made to restore the anti-sheep red blood cell (RBC) and plant lectin mitogenic responses of long-lived, aging BC3F1 and B6D2F1 hybrid mice by grafting syngeneic (a) bone marrow cells from young mice, (b) thymus from newborn mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4453055241185769424c569f2a7ca03
https://doi.org/10.1016/0090-1229(76)90046-5
https://doi.org/10.1016/0090-1229(76)90046-5