Zobrazeno 1 - 3
of 3
pro vyhledávání: '"T M Leber"'
Autor:
A J H Gearing, P Beckett, M Christodoulou, M Churchill, J M Clements, M Crimmin, A H Davidson, A H Drummond, W A Gallowav, R Gilbert, J L Gordon, T M Leber, M Mangan, K Miller, P Nayee, K Owen, S Patel, W Thomas, G Wells, L M Wood, K Woolley
Publikováno v:
Journal of Leukocyte Biology. 57:774-777
Tumor necrosis factor-α (TNF-α) is released from a cell membrane-anchored precursor by proteolytic cleavage. We have shown that broad spectrum synthetic inhibitors of matrix metalloproteinases (MMPs) prevent the processing of the TNF precursor but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca17bbfc3fd889e26ae48562e493a49
https://doi.org/10.1002/jlb.57.5.774
https://doi.org/10.1002/jlb.57.5.774
Autor:
T M, Leber, R P, Negus
Publikováno v:
Methods in molecular medicine. 39
Matrix metalloproteases (MMPs) are a family of structurally and functionally related endopeptidases. They have in common a zinc ion at the active site and are released as an inactive proform (zymogen). Proteolytic activation enables MMPs to degrade c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dff26e34a951a641df46fabaf5f4fcad
https://pubmed.ncbi.nlm.nih.gov/21340807
https://pubmed.ncbi.nlm.nih.gov/21340807
Autor:
W. A. Galloway, J. L. Gordon, M Churchill, W. Thomas, John M. Clements, MH Mangan, Paul Beckett, Alan H. Davidson, Katharine R. Owen, Sandip Patel, Andrew J. H. Gearing, P. Nayee, T. M. Leber, Graham Wells, L. M. Wood, Robert J.C. Gilbert, M. Christodoulou, K. Woolley, Alan H. Drummond, Keith W. Miller
Publikováno v:
Nature. 370(6490)
Tumour necrosis factor-alpha (TNF-alpha) is a potent pro-inflammatory and immunomodulatory cytokine implicated in inflammatory conditions such as rheumatoid arthritis, Crohn's disease, multiple sclerosis and the cachexia associated with cancer or hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a1a096589d2b1a436ce51c34861282
https://pubmed.ncbi.nlm.nih.gov/8052310
https://pubmed.ncbi.nlm.nih.gov/8052310