Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: Evidence from population sample stratified for polygenic risk

Autor: S I Dimitriadis, G Perry, T M Lancaster, K E Tansey, K D Singh, P Holmans, A Pocklington, G Davey Smith, S Zammit, J Hall, M C O’Donovan, M J Owen, D K Jones, D E Linden

Publikováno v: Cerebral Cortex, 33:bhac256, 2997-3011. Oxford University Press
Dimitriadis, S L, Perry, G, Lancaster, T, Tansey, K, Singh, K D, Holmans, P, Pocklington, A, Davey Smith, G, Zammit, S, Hall, J, O'Donovan, M C, Owen, MJ, Jones, D K & Linden, DE 2022, ' Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis : Evidence from population sample stratified for polygenic risk ', Cerebral Cortex . https://doi.org/10.1093/cercor/bhac256

Research studies based on tractography have revealed a prominent reduction of asymmetry in some key white-matter tracts in schizophrenia (SCZ). However, we know little about the influence of common genetic risk factors for SCZ on the efficiency of ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfa0fe20520b86b5351b76d5506a230

COMT Val(158) Met genotype is associated with reward learning: a replication study and meta-analysis

Autor: N S, Corral-Frías, D A, Pizzagalli, J M, Carré, L J, Michalski, Y S, Nikolova, R H, Perlis, J, Fagerness, M R, Lee, E Drabant, Conley, T M, Lancaster, S, Haddad, A, Wolf, J W, Smoller, A R, Hariri, R, Bogdan

Publikováno v: Genes, brain, and behavior. 15(5)

Identifying mechanisms through which individual differences in reward learning emerge offers an opportunity to understand both a fundamental form of adaptive responding as well as etiological pathways through which aberrant reward learning may contri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2929a9c42879560519e3908c6304fad8
https://pubmed.ncbi.nlm.nih.gov/27138112

CACNA1C risk variant affects reward responsiveness in healthy individuals

Autor: T M, Lancaster, E A, Heerey, K, Mantripragada, D E J, Linden

Publikováno v: Translational Psychiatry

The variant at rs1006737 in the L-type voltage-gated calcium channel (alpha 1c subunit) CACNA1C gene is reliably associated with both bipolar disorder and schizophrenia. We investigated whether this risk variant affects reward responsiveness because

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8981290a5284ea2ed5f3fffb2292abb2
https://pubmed.ncbi.nlm.nih.gov/25290268