Zobrazeno 1 - 10
of 40
pro vyhledávání: '"T M Brennan"'
Autor:
Daniel Schirlin, Debra L. Taylor, C. G. Bridges, P. S. Ahmed, J.-M. Hornsperger, Celine Tarnus, A. S. Tyms, V. Van Dorsselaer, T M Brennan
Publikováno v:
Antiviral Chemistry and Chemotherapy. 8:205-214
MDL 74,695, a novel dipeptide-like compound containing the ‘difluorostatone type’ transition state mimic and a potent inhibitor of the human immunodeficiency virus (HIV) proteinase, was investigated for anti-HIV activity in vitro. The compound sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f943e976d09e28100cd46fd398973d7
https://doi.org/10.1177/095632029700800304
https://doi.org/10.1177/095632029700800304
Autor:
H. C. Chui, R. M. Biefeld, B. E. Hammons, W. G. Breiland, T. M. Brennan, E. D. Jones, H. K. Moffat, M. H. Kim, P. Grodzinski, K. H. Chang, H. C. Lee
Publikováno v:
Journal of Electronic Materials. 26:37-42
We have performed an extensive study of GaAs, Al0.22Ga0.78As, and In0.16Ga0.84As grown using tertiarybutylarsine (TBA) in an ultra-high purity metalorganic chemical vapor deposition multi-wafer reactor. Key results include: high purity TBA AlGaAs lay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::864a78d5835318f62ed119b3d77112bf
https://doi.org/10.1007/s11664-997-0131-7
https://doi.org/10.1007/s11664-997-0131-7
Publikováno v:
Antiviral Chemistry and Chemotherapy. 7:253-260
MDL 74968 (9-[2-methylidene-3-(phosphonomethoxy)-propyl]guanine), a novel acyclonucleotide derivative of guanine, inhibited human immunodeficiency virus type 1 (HIV-1) replication in vitro with activity comparable to that of adefovir (PMEA; 9-(2-phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451ceceee9bb58c59713999e498fb867
https://doi.org/10.1177/095632029600700505
https://doi.org/10.1177/095632029600700505
Autor:
J M Hornsperger, A. S. Tyms, J F Navé, C G Bridges, Debra Taylor, P Casara, P S Ahmed, T. M. Brennan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1072-1077
The novel acyclonucleotide derivative of guanine, 9-[2-methylidene-3-(phosphonomethoxy)propyl] guanine (MDL 74,968), had antiviral activity comparable to those of 9-(2-phosphonomethoxyethyl) adenine (PMEA) and 2',3'-dideoxyinosine against laboratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db8c5344accd5aff341bdbd7bf1eacc
https://doi.org/10.1128/aac.40.5.1072
https://doi.org/10.1128/aac.40.5.1072
Publikováno v:
Antiviral Chemistry and Chemotherapy. 6:307-311
The basis of azidothymidine (AZT) insensitivity in the human JM T-cell line has been investigated. It was shown that uptake of radiolabelled thymidine or AZT into cellular acid-soluble pools of JM cells was about 10-fold lower than that seen in AZT-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc9483d912d147262110978d1bca3557
https://doi.org/10.1177/095632029500600504
https://doi.org/10.1177/095632029500600504
Publikováno v:
Antiviral Chemistry and Chemotherapy. 6:143-152
The anti-human immunodeficiency virus type 1 (HIV-1) activity of the α-glucosidase 1 inhibitor 6-0-butanoylcastanospermine (MDL 28574) was assessed in combination with the 2′,3′-dideoxynucleoside analogues zidovudine (AZT), didanosine (ddl) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593b8e597490bef7e981e60f2e2727b0
https://doi.org/10.1177/095632029500600303
https://doi.org/10.1177/095632029500600303
Publikováno v:
Journal of Applied Physics. 76:7907-7914
The effects of built‐in biaxial strain on Γ‐X transport in n‐GaAs/i‐InxAl1−xAs/n‐GaAs pseudomorphic single‐barrier structures (x=0, 0.03, and 0.06) are studied by measuring temperature‐dependent I‐V characteristics. For the accurat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771eb61dd70cd7403d11267f091af51e
https://doi.org/10.1063/1.357901
https://doi.org/10.1063/1.357901
Publikováno v:
Antiviral Research. 25:169-175
The intercellular adhesion molecule (ICAM-1, CD54) and its counter receptor, the integrin leukocyte function associated antigen 1 (LFA-1, CD11a/CD18), have important roles in the immune response. These include guiding leukocytes to sites of inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a527cac8cef4998ad1590a162c7bcb44
https://doi.org/10.1016/0166-3542(94)90105-8
https://doi.org/10.1016/0166-3542(94)90105-8
Autor:
S. R. Kurtz, T.J. Drummond, J. A. Olsen, B. E. Hammons, A. J. Howard, I. J. Fritz, T. M. Brennan
Publikováno v:
Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films. 12:1003-1008
Using atomic force microscopy (AFM), we have investigated the effects of growth temperature and dopant incorporation on the surface morphology of molecular beam epitaxy grown graded buffer layers and strained layer superlattices (SLSs) in the InGaAlA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::530e490db420506a46725a904efeb350
https://doi.org/10.1116/1.579275
https://doi.org/10.1116/1.579275
Autor:
T M Brennan, Celine Tarnus, D. Janowick, A. S. Tyms, S. Baltzer, F. Weber, V. Van Dorsselaer, D.L. Taylor, J.M. Remy, Daniel Schirlin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1213-1218
Replacement of the benzylamine carboxy terminus with a (R)-valinol ether carboxy terminus confers high inhibitory activity to derivatives of the difluorostatone and even difluorostatine types against HIV-1 protease. In HIV infected cells, the difluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e290279510467f5a187fafb7ecea9de2
https://doi.org/10.1016/s0960-894x(01)80332-2
https://doi.org/10.1016/s0960-894x(01)80332-2