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Verrucous carcinoma in epidermolysis bullosa simplex is possibly associated with a novel mutation in the keratin 5 gene

Autor: H, Schumann, W, Roth, C, Has, A, Volz, C, Erfurt-Berge, T M, Magin, L, Bruckner-Tuderman

Publikováno v: The British journal of dermatology. 167(4)

Epidermolysis bullosa simplex (EBS) is mainly caused by mutations in the KRT5 and KRT14 genes. Squamous cell carcinoma (SCC) represents the second most frequent skin neoplasia with complex aetiology. The molecular events disrupting the orchestrated i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a3469d3de24493ceb3ede1dc6854a2b
https://pubmed.ncbi.nlm.nih.gov/22639907

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Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18

Autor: M, Hesse, T M, Magin, K, Weber

Publikováno v: Journal of cell science. 114(Pt 14)

We screened the draft sequence of the human genome for genes that encode intermediate filament (IF) proteins in general, and keratins in particular. The draft covers nearly all previously established IF genes including the recent cDNA and gene additi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53db4c716c098ae9a48a275110ff432c
https://pubmed.ncbi.nlm.nih.gov/11683385

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Lessons from keratin transgenic and knockout mice

Autor: T M, Magin

Publikováno v: Sub-cellular biochemistry. 31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e73688beff87c34939c2dec8c443f751
https://pubmed.ncbi.nlm.nih.gov/9932492

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De novo formation of cytokeratin filaments in calf lens cells and cytoplasts after transfection with cDNAs or microinjection with mRNAs encoding human cytokeratins

Autor: T M, Magin, B L, Bader, M, Freudenmann, W W, Franke

Publikováno v: European journal of cell biology. 53(2)

We have studied the formation of new intermediate-sized filaments (IFs) by human cytokeratins (CKs) 8 and/or 19 in cultured bovine lens cells stably transfected with the corresponding cDNAs under SV40 promoter control. In the transfected cells, polyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b4422a4b5a8917688361d708c98855e
https://pubmed.ncbi.nlm.nih.gov/1706999

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The hemidesmosomal plaque. I. Characterization of a major constituent protein as a differentiation marker for certain forms of epithelia

Autor: K, Owaribe, J, Kartenbeck, S, Stumpp, T M, Magin, T, Krieg, L A, Diaz, W W, Franke

Publikováno v: Differentiation; research in biological diversity. 45(3)

To examine whether constituent proteins of hemidesmosomal structures can be used as markers for certain pathways of epithelial differentiation we have examined the occurrence of the major M- approximately 230,000 plaque protein, the "bullous pemphigo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4cfc3c5d99dc33991d65f26b731e2df
https://pubmed.ncbi.nlm.nih.gov/2090522

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Cytokeratin expression in simple epithelia. II. cDNA cloning and sequence characteristics of bovine cytokeratin A (no. 8)

Autor: T M, Magin, J L, Jorcano, W W, Franke

Publikováno v: Differentiation; research in biological diversity. 30(3)

Cytokeratin A (no. 8) is a cytoskeletal protein (Mr, approximately 53,000 in bovine cells) which is typical of all simple epithelia, is widespread in all cultured epithelial cells, and together with its partner cytokeratin D, is the first cytokeratin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c682072d9dbeb7cdd88c6ed00c81fdc
https://pubmed.ncbi.nlm.nih.gov/2422084

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