Zobrazeno 1 - 10
of 22
pro vyhledávání: '"T M, Kuzel"'
Autor:
B A, Carneiro, K A, Collier, R J, Nagy, S, Pamarthy, V, Sagar, S, Fairclough, J, Odegaard, R B, Lanman, R, Costa, T, Taxter, T M, Kuzel, A, Fan, Y K, Chae, M, Cristofanilli, M H, Hussain, S A, Abdulkadir, F J, Giles
Publikováno v:
JCO Precis Oncol
PARP1/2 inhibitors are effective against BRCA2-deficient tumors. The PARP inhibitor (PARPi) olaparib received FDA breakthrough designation for treatment of metastatic castration-resistant prostate cancers (CRPC) carrying mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf03688ddd68af2dcd1e3fabae52ccd9
https://pubmed.ncbi.nlm.nih.gov/32913984
https://pubmed.ncbi.nlm.nih.gov/32913984
Publikováno v:
Journal of Clinical Oncology. 18:2152-2168
PURPOSE: Primary cutaneous B-cell lymphoma (PCBCL) has only recently been recognized as a distinct clinical entity. With the advent of improved immunophenotyping and immunogenotyping, increasing numbers of PCBCL cases are being diagnosed. However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd6c7e14f34e97563e7945cb4b47094
https://doi.org/10.1200/jco.2000.18.10.2152
https://doi.org/10.1200/jco.2000.18.10.2152
Publikováno v:
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 143(1)
Mycosis fungoides is typified by a cutaneous infiltrate of CD4+ lymphocytes with a Th2 phenotype. As the disease advances, there is increased expression of Th2 cytokines. This results in a subsequent suppression of Th1 cytokines and impaired cell med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aed7a3257ff3e6c046742a1af788d29c
https://pubmed.ncbi.nlm.nih.gov/18833051
https://pubmed.ncbi.nlm.nih.gov/18833051
Autor:
T M, Kuzel
Publikováno v:
Clinical lymphoma. 1
Clinical trials of DAB(389)IL-2 (denileukin diftitox, ONTAK) have been conducted in a variety of disease states as well as in normal volunteers. The individuals treated include 45 volunteers in pharmacokinetic testing, 195 patients with noncancer ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0bc6460ad29d4a6d207fe8d8c829a6f5
https://pubmed.ncbi.nlm.nih.gov/11707861
https://pubmed.ncbi.nlm.nih.gov/11707861
Autor:
M E, Dolan, B L, McRae, E, Ferries-Rowe, M, Belanich, G A, van Seventer, J, Guitart, D, Pezen, T M, Kuzel, D B, Yarosh
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(8)
Mycosis fungoides is a low-grade cutaneous T-cell lymphoma. Early treatment often involves the use of topical chemotherapy such as mechlorethamine or carmustine although single-agent oral chemotherapy with alkylators is common for advanced disease. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75414160166488f57c38e2c1ec51c6da
https://pubmed.ncbi.nlm.nih.gov/10473086
https://pubmed.ncbi.nlm.nih.gov/10473086
Publikováno v:
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 8(3)
Multi-attribute utility theory (MAUT) provides a way to model decisions involving trade-offs among different aspects or goals of a problem. We used MAUT to model prostate cancer patients' preferences for their own health state and we compared this mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b464e382d3efd672caf330bb4b05a4ab
https://pubmed.ncbi.nlm.nih.gov/10472149
https://pubmed.ncbi.nlm.nih.gov/10472149
Autor:
F M, Foss, T M, Kuzel
Publikováno v:
Cancer treatment and research. 99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::806c6a630d0770fd7efd848672622177
https://pubmed.ncbi.nlm.nih.gov/9891869
https://pubmed.ncbi.nlm.nih.gov/9891869
Publikováno v:
Journal of clinical immunology. 18(3)
DAB389IL-2 is a recombinant fusion toxin composed of the diphtheria A chain and a protion of the translocating region of the diphtheria B chain, replacing the receptor binding domain with human IL-2. DAB389IL-2 can be safely administered to humans wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::888288ed7e14362ef177493bce160437
https://pubmed.ncbi.nlm.nih.gov/9624582
https://pubmed.ncbi.nlm.nih.gov/9624582
Autor:
L R, Kong, C F, Huang, D, Hakimian, D, Variakojis, L, Klein, T M, Kuzel, L I, Gordon, C, Zanzig, E, Wollins, M S, Tallman
Publikováno v:
Cancer. 82(5)
The aim of this study was to determine the long term outcome and toxicities after the administration of 2-chlorodeoxyadenosine (2-CdA) to patients with previously treated, advanced, indolent non-Hodgkin's lymphoma (NHL).Twenty-two patients (median ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c19ecc60093f4cab4642470a99d1faab
https://pubmed.ncbi.nlm.nih.gov/9921999
https://pubmed.ncbi.nlm.nih.gov/9921999
Autor:
C F, LeMaistre, M N, Saleh, T M, Kuzel, F, Foss, L C, Platanias, G, Schwartz, M, Ratain, A, Rook, C O, Freytes, F, Craig, J, Reuben, J C, Nichols
Publikováno v:
Blood. 91(2)
The purpose of this study was to evaluate the safety, tolerability, pharmacokinetics, and possible antitumor activity of a ligand fusion-protein, DAB389IL-2, in a phase I trial. This was a multicenter, open-label, dose-escalation trial. Patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b36c5a11eaa8f10209aadeff94db86f
https://pubmed.ncbi.nlm.nih.gov/9427692
https://pubmed.ncbi.nlm.nih.gov/9427692