Zobrazeno 1 - 3
of 3
pro vyhledávání: '"T M, Judge"'
Autor:
Sharon N. Bisaha, Alice H. Lin, Donn G. Wishka, W R Humphrey, T M Judge, C S Jacob, N L Olds, Joel Morris, Ronald B. Gammill, A L Wiltse
Publikováno v:
Journal of Medicinal Chemistry. 36:2026-2032
The synthesis and biological evaluation of a series of antiplatelet 2-morpholinylchromones has been described. Modification of the C-7 phenylmethoxy group of 8-methyl-7-(phenylmethoxy)-2-(4-morpholinyl)-4H-1-benzopyran-4-one (2) has led to the discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf06f4f6a3df0a0fb137c31c3a18b52d
https://doi.org/10.1021/jm00066a012
https://doi.org/10.1021/jm00066a012
Publikováno v:
Molecular pharmacology. 44(4)
We discovered the ability of U-93631 (4-dimethyl-3-t-butylcarboxyl-4,5- dihydro[1,5-a]imidazoquinoxaline) to accelerate decay of gamma-aminobutyric acid (GABA)-induced currents, and we explored its mechanism in human embryonic kidney cells (HEK-293)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf6d7140d2ec8083c23192e648a951e1
https://pubmed.ncbi.nlm.nih.gov/8232235
https://pubmed.ncbi.nlm.nih.gov/8232235
Substituted pyrazinones, a new class of allosteric modulators for gamma-aminobutyric acidA receptors
Publikováno v:
Molecular pharmacology. 44(2)
We discovered substituted pyrazinones as a new class of allosteric modulators of gamma-aminobutyric acid (GABA)A receptors. Prototype pyrazinones, U-92813 [1-(furfuryl)-3,5-dichloro-6-phenylpyrazinone] and U-94863 [1-benzyl-3,5-dichloro-6-(2-chloroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6285b769e64bfcd32e4402701f00c88
https://pubmed.ncbi.nlm.nih.gov/8018215
https://pubmed.ncbi.nlm.nih.gov/8018215