Zobrazeno 1 - 10
of 17
pro vyhledávání: '"T M, Iverson"'
Autor:
Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova, Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova, Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Kristyna Cunatova, Tomas Mracek, Hans K. Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini, T. M. Iverson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Complex II (CII) activity controls phenomena that require crosstalk between metabolism and signaling, including neurodegeneration, cancer metabolism, immune activation, and ischemia-reperfusion injury. CII activity can be regulated at the le
Externí odkaz:
https://doaj.org/article/a63f5096183a4241a866d4154beb8b16
Autor:
Barbara A. Bensing, Haley E. Stubbs, Rupesh Agarwal, Izumi Yamakawa, Kelvin Luong, Kemal Solakyildirim, Hai Yu, Azadeh Hadadianpour, Manuel A. Castro, Kevin P. Fialkowski, KeAndreya M. Morrison, Zdzislaw Wawrzak, Xi Chen, Carlito B. Lebrilla, Jerome Baudry, Jeremy C. Smith, Paul M. Sullam, T. M. Iverson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Streptococcal siglec-like binding regions (SLBRs) selectively bind cell surface glycans, but the basis for this selectivity is not understood. Here, the authors identify selectivity-modulating SLBR regions and study how changes in SLBR glycan selecti
Externí odkaz:
https://doaj.org/article/b700213795704bd98ce0a30827b2135e
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285343 (2023)
The flagellar motor supports bacterial chemotaxis, a process that allows bacteria to move in response to their environment. A central feature of this motor is the MS-ring, which is composed entirely of repeats of the FliF subunit. This MS-ring is cri
Externí odkaz:
https://doaj.org/article/fbff2c4cfa3f490d92bd8c36009427d3
Autor:
Rachana Tomar, Irina G Minko, Pankaj Sharma, Andrew H Kellum, Li Lei, Joel M Harp, T M Iverson, R Stephen Lloyd, Martin Egli, Michael P Stone
Publikováno v:
Nucleic Acids Research. 51:3754-3769
The N-(2-deoxy-d-erythro-pentofuranosyl)-urea DNA lesion forms following hydrolytic fragmentation of cis-5R,6S- and trans-5R,6R-dihydroxy-5,6-dihydrothymidine (thymine glycol, Tg) or from oxidation of 7,8-dihydro-8-oxo-deoxyguanosine (8-oxodG) and su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb5f1f87aea913de54b53daf99c3e04
https://doi.org/10.1093/nar/gkad164
https://doi.org/10.1093/nar/gkad164
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA
Externí odkaz:
https://doaj.org/article/a973f3002bed4ac7835c55391dc6a46c
Autor:
Qiuyan Chen, Nicole A. Perry, Sergey A. Vishnivetskiy, Sandra Berndt, Nathaniel C. Gilbert, Ya Zhuo, Prashant K. Singh, Jonas Tholen, Melanie D. Ohi, Eugenia V. Gurevich, Chad A. Brautigam, Candice S. Klug, Vsevolod V. Gurevich, T. M. Iverson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
While arrestins are mainly associated with GPCR signaling, arrestin-3 can signal independently of receptor interaction. Here the authors present the structure of arrestin-3 bound to inositol hexakisphosphate (IP6) and propose a model for arrestin-3 a
Externí odkaz:
https://doaj.org/article/5669fd07492147f39e3967f45e7f0f53
Autor:
Barbara A Bensing, Liang Li, Olga Yakovenko, Maurice Wong, Karen N Barnard, T M Iverson, Carlito B Lebrilla, Colin R Parrish, Wendy E Thomas, Yan Xiong, Paul M Sullam
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007896 (2019)
Streptococcus gordonii and Streptococcus sanguinis are primary colonizers of the tooth surface. Although generally non-pathogenic in the oral environment, they are a frequent cause of infective endocarditis. Both streptococcal species express a serin
Externí odkaz:
https://doaj.org/article/964386ae85dc41faa7291b4b33f7e9d0
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215140 (2019)
Lyn kinase (Lck/Yes related novel protein tyrosine kinase) belongs to the family of Src-related non-receptor tyrosine kinases. Consistent with physiological roles in cell growth and proliferation, aberrant function of Lyn is associated with various f
Externí odkaz:
https://doaj.org/article/4bc342318ad8404a872fac60cdacaeac
Autor:
Breann L, Brown, T M, Iverson
Publikováno v:
Nature chemical biology
The covalent attachment of one or multiple heme cofactors to their protein chain enables cytochromes c to be utilized in electron transfer and redox catalysis in extracytoplasmic environments. A dedicated heme maturation machinery, whose core compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba51a57fa1ef08424db30523e6686222
https://pubmed.ncbi.nlm.nih.gov/33958791
https://pubmed.ncbi.nlm.nih.gov/33958791