Zobrazeno 1 - 10
of 55
pro vyhledávání: '"T M, Griffith"'
Autor:
T. M. Griffith, M. A. Watson
Publikováno v:
Journal of Evolutionary Biology. 18:1601-1612
Adaptation to local environments may be an important determinant of species’ geographic range. However, little is known about which traits contribute to adaptation or whether their further evolution would facilitate range expansion. In this study,
Publikováno v:
British Journal of Pharmacology. 141:374-384
Correction to: British Journal of Pharmacology (2003) 140, 1261–1271. doi:10.1038/sj.bjp.0705556 We have compared the effects of ouabain on the maintenance of gap junctional communication in rat aortic A7r5 smooth muscle cells, monkey COS-1 fibrobl
Autor:
William Howard Evans, Michael D. Randall, Patricia E. M. Martin, T. M. Griffith, David A. Kendall, David Harris
Publikováno v:
European Journal of Pharmacology. 402:119-128
We have examined the effects of ouabain (1 mM), the gap junction inhibitors, 18 alpha-glycyrrhetinic acid (100 microM), N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride (SR141716A; 10 micr
Autor:
T. M. Griffith, Michael D. Randall, Andrew Chaytor, William Howard Evans, Patricia E. M. Martin
Publikováno v:
The Journal of Physiology. 520:539-550
1. We have shown that the endocannabinoid anandamide and its stable analogue methanandamide relax rings of rabbit superior mesenteric artery through endothelium-dependent and -independent mechanisms that are unaffected by blockade of NO synthase and
Autor:
I R Hutcheson, M R Pitman, Robertson Towart, J. O. G. Karlsson, T M Griffith, H. Refsum, M. Gregersen
Publikováno v:
British Journal of Pharmacology. 128:451-457
1 We have used isolated arterial preparations from the rabbit and dog to investigate whether non-ionic iodinated radiographic contrast media (IRCM) modulate nitric oxide (NO) release. The tri-iodinated monomers iopromide and iohexol were compared wit
Publikováno v:
Circulation Research. 84:53-63
Abstract —NO- and prostanoid-independent relaxations are generally assumed to be mediated by an endothelium-derived hyperpolarizing factor (EDHF) that has been postulated to be an arachidonic acid metabolite. Recent evidence also suggests that dire
Autor:
T. M. Griffith, Rodney S. Berman
Publikováno v:
British Journal of Pharmacology. 124:1245-1253
1. Using an X-ray microangiographic technique in rabbit isolated perfused ears preconstricted with 5-HT (300 nM) and histamine (300 nM), we investigated the combined actions of N(omega)-nitro-L-arginine methyl ester (L-NAME) and indomethacin on acety
Autor:
Iain Robert Hutcheson, T. M. Griffith
Publikováno v:
British Journal of Pharmacology. 122:117-125
1 We have used a cascade bioassay system and isolated arterial ring preparations to investigate the contribution of Ca2+ release from endothelial intracellular stores to nitric oxide (NO) production evoked by increases in shear stress and by acetylch
Publikováno v:
The Journal of Physiology. 503:99-110
1. Phenylephrine (10 microM) evoked rises in tension in isolated rings of endothelium-denuded rabbit superior mesenteric artery. These increases consisted of a tonic component with superimposed rhythmic activity, the frequency of which generally rema
Autor:
Rodney S. Berman, T. M. Griffith
Publikováno v:
British Journal of Pharmacology. 120:639-646
1. By use of rabbit isolated perfused intact ears and isolated perfused segments of central and first generation daughter branch ear arteries, we investigated the actions of charybdotoxin (ChTX), a blocker of calcium-activated K+ channels (KCa channe